Wei Xue PhD

Professor of Chemistry

Doctoral Supervisor

State Key Laboratory of Green Pesticides 

Contact details

Room 201, Science Building, Center for Research and Development of Fine Chemicals, Guizhou University, East Campus, Guizhou University, China

Email wxue@gzu.edu.cn

Phone +86 851-88292090

Qualifications

BSc – Guizhou Normal University, Guiyang, Guizhou, China 1992

MSc – Guizhou University, Guiyang, Guizhou, China 2005

PhD – Guizhou University, Guiyang, Guizhou, China 2011

Selected Positions held

2012-present Professor – Guizhou University, China

2007-2012 Associate Professor – Guizhou University, China

2005-2007 Lecturer – Guizhou University, China

Profile

Professor Xue is an esteemed scholar in the domain of fine chemical engineering, with a distinguished reputation for his contributions to green drug design and synthesis, as well as innovative development of new pesticides from natural sources. His pioneering work has significantly propelled the field of pesticide science forward, enhancing both the efficacy and safety of pesticides while simultaneously promoting environmental sustainability and ecological balance. Funded by the National Natural Science Foundation of China, Professor Xue has taken the lead in research initiatives that delve into the intricate design, synthesis, and biological activity of chalcone and myricetin derivatives. These projects not only exemplify his leadership in scientific inquiry but also underscore his commitment to fostering advancements that align with environmental and health-conscious agendas.

Selected research grants 

1. National Natural Science Foundation of China (32072446)

2. National Natural Science Foundation of China (21867003)

Selected recent publications (*corresponding authors)

1. Feng Peng, Tingting Liu, Yunying Zhu, Fang Liu, Xiao Cao, Qifan Wang, Liwei Liu, Wei Xue*, Novel 1,3,4-oxadiazole sulfonate/carboxylate flavonoid derivatives: Synthesis and biological activity, Pest Management Science, 2023, 79(1), 274-283.

2. Wenliang Zhan, Piao Mao, Chunmei Yuan, Tao Zhang, Yi Liu, Jiao Tian, Wei Xue*, Design, synthesis, and antiviral activities of chalcone derivatives containing pyrimidine,Journal of Saudi Chemical Society, 2023, 27, 101590.

3. Nan Sun, Yuchen Gong, Yuanxiang Zhou, Yuanquan Zhang, Nian Zhang, Li Xing, Wei Xue*, Design, synthesis and bioactivity of chalcone derivatives containing indanone, ACS Omega, 2023, 8(2), 2556-2563.

4. Xiao Cao, Fang Liu, Bangcan He, Li Xing, Yuanquan Zhang, Nian Zhang, Wei Xue*, Design, synthesis, bioactivity and mechanism of action of novel myricetin derivatives containing amide and hydrazide, Arabian Journal of Chemistry, 2023, 16,104588.

5. Ran Zhou, Wenliang Zhan, Chunmei Yuan, Tao Zhang, Piao Mao, Zhiling Sun, Yousan An, Wei Xue*, Design, Synthesis and Antifungal Activity of 1, 4-pentadiene-3-one Containing Quinazolinon, International Journal of Molecular Sciences, 2023, 24, 2599.

6. Die Hu, Nian Zhang, Qing Zhou, Yuanxiang Zhou, Chenyu Gong, Yuanquan Zhang, Wei Xue*, Synthesis and biological activities of novel chalcone derivatives containing pyrazole oxime ethers, Fitoterapia, 2023, 166, 105458.

7. Xiao Cao, Bangcan He, Fang Liu, Yuanquan Zhang, Li Xing, Nian Zhang, Yuanxiang Zhou, Chenyu Gong, and Wei Xue*, Design, Synthesis and Bioactivity of Myricetin Derivatives Containing Isoxazole Skeleton, RSC Advances, 2023, 13, 6459.

8. Die Hu, Nian Zhang, Yuanquan Zhang, Chunmei Yuan, Chenyu Gong, Yuanxiang Zhou, Wei Xue*, Design, synthesis and biological activity of novel chalcone derivatives containing indole, Arabian Journal of Chemistry，2023, 16, 104776.

9. Fang Liu, Xiao Cao, Li Xing, Bangcan He, Jiao Tian, Yi Liu, Zhiling Sun, Wei Xue*, Design, Synthesis, Biological Activity Evaluation and Action Mechanism of Myricetin Derivatives Containing Thiazolebisamide, Chem Biodiversty, 2023, 20 e202201103.

10. Shuai Chen, Miaohe Zhang, Shuang Feng, Chenyu Gong, Yuanxiang Zhou, Li Xing, Bangcan He, Yongjun Wu*, Wei Xue*, Design, synthesis and biological activity of chalcone derivatives containing pyridazine, Arabian Journal of Chemistry, 2023, 16, 104852

11. Yihui Wang, Ran Zhou, Nan Sun, Ming He, Yongjun Wu & Wei Xue*, Synthesis and antibacterial activity of novel 1,4-pentadien-3-one derivatives bearing a benzothiazole moiety, Journal of Heterocyclic Chemistry, 2022, 59, 533-542.

12. Xuemei Tang‡ , Qing Zhou‡, Wenliang Zhana, Die Hua, Ran Zhoua, Nan Suna, Shuai Chena, Wenneng Wu, Wei Xue*, Synthesis of novel antibacterial and antifungal quinoxaline derivatives, RSC Advances, 2022, 12, 2399-2407.

13. Qing Zhou, Xuemei Tang, Shuai Chen, Wenliang Zhan, Die Hu, Ran Zhou, Nan Sun, YongJun Wu, Wei Xue*, Design, Synthesis and Antifungal Activity of Novel Chalcone Derivatives Containing Piperazine Fragment, Journal of Agricultural and Food Chemistry, 2022,70(4), 1029-1036.

14. Feng Peng, Tingting Liu, Xiao Cao, Qifan Wang, Fang Liu, Liwei Liu, Ming He, Wei Xue*, Antiviral Activities of Novel Myricetin Derivatives Containing 1,3,4-Oxadiazole Bisthioether, Chemical Biodiversity, 2022, 19, e202100939.

15. Tingting Liu, Feng Peng, Yunying Zhu, Xiao Cao, Qifan Wang, Fang Liu, Liwei Liu, Wei Xue*, Design, synthesis, biological activity evaluation and mechanism of action of myricetin derivatives containing thioether quinazolinone, Arabian Journal of Chemistry, 2022, 15, 104019.

16. Xuemei Tang, Wenliang Zhan, Shuai Chen, Ran Zhou, Die Hu, Nan Sun, Qiang Fei, Wenneng Wu, Wei Xue*, Synthesis, Bioactivity and Preliminary Mechanism of Action of Novel Trifluoromethyl Pyrimidine Derivatives, Arabian Journal of Chemistry, 2022,15, 104110.

17. Qing Zhou, Yuanxiang Zhou, Yunying Zhu, Chenyu Gong, Yongjun Wu*, Wei Xue*, Design, synthesis, and biological evaluation of novel 1,4-pentadien-3-one derivatives containing sulfonamide moiety, Journal of Agricultural and Food Chemistry, 2022, 70, 51, 16096-16105.

Selected patents

1. Xue Wei, Tingting Liu, Junhu Qin, Peng Feng, Cao Xiao, Qifan Wang, Liu Fang, Liwei Liu, He Ming, A Myricetin Derivative Containing Quinazolin-4(3H)-one and Its Preparation Method and Application, Chinese Invention Patent: ZL 202111093408.4, Application Date: September 17, 2021, Grant Date: March 31, 2023

2. Xue Wei, Peng Feng, Tingting Liu, Qifan Wang, Liu Fang, Cao Xiao, Yuanxiang Zhou, Gong Chenyu, Xu Xuan, Liwei Liu, He Ming, Lu Ping, Myricetin Derivative of 1,3,4-Oxadiazole Thioether Sulfonate, Preparation Method, and Its Use, Chinese Invention Patent: ZL 202210022958.5, Application Date: January 10, 2022, Grant Date: April 7, 2023

3. Xue Wei, Zhou Qing, Chen Shuai, Wenliang Zhan, Hu Die, Sun Nan, Zhou Ran, Yuanxiang Zhou, Chunmei Yuan, Chenyu Gong, Xing Li, Mao Piao, Zhang Tao, Zhang Nian, Bangcan He, Tian Jiao, Liu Yi, A Chalcone Derivative Containing Sulfonyl Piperazine and Its Preparation Method and Application, Chinese Invention Patent: ZL 202111445800.0, Application Date: December 1, 2021, Grant Date: April 21, 2023

4. Xue Wei, Peng Feng, Qin Junhu, Liu Tingting, Wang Qifan, Liu Fang, Cao Xiao, Liu Liwei, He Ming, Myricetin Derivative of 1,3,4-Oxadiazole Thioether, Preparation Method, and Its Use, Chinese Invention Patent: ZL 202110793881.7, Application Date: July 14, 2021, Grant Date: April 18, 2023

5. Xue Wei, He Jun, Shitao Yin, Zhou Qing, Xuemei Tang, Tingting Liu, Peng Feng, He Ming, Myricetin Derivative Containing Quinazoline, Its Preparation Method, and Its Use, Chinese Invention Patent: ZL 202011082248.9, Application Date: October 12, 2020, Grant Date: April 18, 2023

6. Xue Wei, Zhang Cheng, Lijuan Chen, Chen Ying, Shichun Jiang, Guo Tao, Rongjiao Xia, Tang Xu, Xiangyang Li, He Ming, A Myricetin Derivative Containing Amide Oxadiazole, Its Preparation Method, and Use, Chinese Invention Patent: ZL 201811232349.2, Application Date: October 23, 2018, Grant Date: February 15, 2022

7. Xue Wei, Chen Ying, Li Pu, Guo Tao, Rongjiao Xia, Chen Mei, Shichun Jiang, He Jun, Shijun Su, Wang Jun, A 1,4-Pentadien-3-one Derivative Containing Thioether Triazole, Its Preparation Method, and Use, Chinese Invention Patent: ZL 201910077841.5, Application Date: January 28, 2019, Grant Date: February 15, 2022

8. Xue Wei, Chen Ying, Shichun Jiang, Chen Mei, Shijun Su, He Jun, Guo Tao, Rongjiao Xia, Wang Jun, He Ming, A Chalcone Derivative Containing Thioether Triazole, Its Preparation Method, and Use, Chinese Invention Patent: ZL 201910249124.6, Application Date: March 29, 2019, Grant Date: March 18, 2022

9. Xue Wei, Li Pu, Chen Ying, Zhang Min, Meimei Jin, Xianfu Tang, Wang Lan, He Ming, A Myricetin Derivative of Thioether-Containing Triazole Schiff Base, Its Preparation Method, and Use, Chinese Invention Patent: ZL 201811476187.7, Application Date: December 4, 2018, Grant Date: March 29, 2022

10. Xue Wei, Xia Rongjiao, Guo Tao, He Jun, Chen Mei, Su Shijun, Tang Xu, Jiang Shichun, Chen Ying, He Ming, Preparation and Use of Quinoxaline-Containing Chalcone Derivatives, Chinese Invention Patent: ZL 201910261427.X, Application Date: April 2, 2019, Grant Date: April 19, 2022

11. Xue Wei, Yihui Wang, Shichun Jiang, Chen Ying, Rongjiao Xia, Guo Tao, Tang Xu, He Ming, Meimei Jin, Li Juan, Benzothiazole-Containing Chalcone Derivatives, Their Preparation Method, and Application, Chinese Invention Patent: ZL 201811148066.X, Application Date: September 29, 2018, Grant Date: April 19, 2022

12. Xue Wei, Yihui Wang, Shichun Jiang, Chen Ying, Rongjiao Xia, Guo Tao, Tang Xu, He Ming, Juping Zhang, 1,4-Pentadien-3-one Derivatives Containing Benzothiazole, Their Preparation Method, and Application, Chinese Invention Patent: ZL 201811148062.1, Application Date: September 29, 2018, Grant Date: March 29, 2022

13. Xue Wei, Tang Xu, Shijun Su, He Jun, Chen Mei, Rongjiao Xia, Guo Tao, Chen Ying, Jiaxiang Wu, Wang Jun, 1,2,4-Triazine-Containing Chalcone Derivatives, Their Preparation Method, and Application, Chinese Invention Patent: ZL 201910106448.4, Application Date: February 2, 2019, Grant Date: April 19, 2022

14. Xue Wei, Tang Xu, Chen Mei, He Jun, Shijun Su, Jiaxiang Wu, Liwei Liu, He Ming, Wang Jun, A Pentadienone Derivative Containing Triazine, Its Preparation Method, and Uses, Chinese Invention Patent: ZL 201910449787.2, Application Date: May 27, 2019, Grant Date: March 25, 2022

15. Xue Wei, Rongjiao Xia, Guo Tao, Chen Mei, Shijun Su, He Jun, Tang Xu, Shichun Jiang, Chen Ying, He Ming, A Quinoxaline-Containing Pentadienone Oxime Ether Compound and Its Preparation Method and Application, Chinese Invention Patent: ZL 201910520064.7, Application Date: June 17, 2019, Grant Date: March 25, 2022

16. Xue Wei, Yihui Wang, Shichun Jiang, Chen Ying, Guo Tao, Rongjiao Xia, Tang Xu, He Ming, Li Juan, Meimei Jin, A Coumarin-Containing Chalcone Derivative, Its Preparation Method, and Application, Chinese Invention Patent: ZL 201811148917.0, Application Date: September 29, 2018, Grant Date: June 21, 2022

17. Xue Wei, Chen Mei, Shitao Yin, Wenliang Zhan, Hu Die, Zhou Ran, He Ming, Lu Ping, A Myricetin Derivative Containing Benzimidazole Sulfonamide, Its Preparation Method, and Uses, Chinese Invention Patent: ZL 202011277100.0, Application Date: November 16, 2020, Grant Date: August 2, 2022

18. Xue Wei, Shijun Su, Shitao Yin, Liu Min, He Ming, Peng Feng, Zhou Qing, Xuemei Tang, Myricetin Derivatives Containing Substituted Pyrimidines, Their Preparation Method, and Uses, Chinese Invention Patent: ZL 202010886013.9, Application Date: August 28, 2020, Grant Date: November 8, 2022

19. Xue Wei, Chen Mei, Liu Min, Shitao Yin, He Ming, Tingting Liu, Xuemei Tang, Peng Feng, A Myricetin Derivative Containing Benzimidazole, Its Preparation Method, and Uses, Chinese Invention Patent: ZL 202010885080.9, Application Date: August 28, 2020, Grant Date: November 8, 2022