Li-Jun Gu PhD

Professor of Organic Chemistry

Doctoral Supervisor

State Key Laboratory of Green Pesticides 

Contact details

Room 330, Jinghua building D, East Campus, Guizhou University

Email ljgu@gzu.edu.cn; gulijun2005@126.com

Phone +86 851-83620521

Qualifications

BSc – Hunan Normal University, China 1998

MSc – Guizhou University, China 2006

PhD – Northwest University, China 2009

Positions held

2009-2017 Associate Professor – Yunnan Minzu University, China

2018-2022 Professor - Yunnan Minzu University, China

2022 – present Professor – Guizhou University, China

Research  

Gu is a nationally renowned organic chemist. His research focuses on electrochemical catalysis C–H functionalization.  C–H functionalization is regarded as a prominent strategy in building-up molecular complexity from simple chemical feedstocks. Achieving C–H functionalizations in this process is by no means an easy task due to the strong bond energy and weak polarity of C–H bonds and the difficulty in distinguishing many C–H bonds in similar chemical environment. Prof. Gu has developed a series of aryl C–H functionalization reactions by electrochemical catalysis and transition metal catalysis, which provide expedient synthesis of the target molecules.

Selected recent publications (*corresponding authors) 

[1]  Gu, L.;*  Jin,C.; Liu, J.; Zhang, H.;  Yuan, M.;* Li, G.  (2016) Acylation of indoles via photoredox catalysis: a route to 3-acylindoles, Green Chem., 18, 1201–1205.

[2] Gu, L.;*  Wang, W.; Liu, J.; Li, G.;  Yuan, M.*  (2016) [bmIm]OH-catalyzed amidation of azides and aldehydes: an efficient route to amides. Green Chem., 18, 2604–2608.

[3] Gu, L.;*  Jin, C.; Wang, W.; He, Y.; Yang,G.; Li,  G.  (2017) Transition-metal-free, visible-light induced cyclization of arylsulfonyl chlorides with o-azidoarylalkynes: a regiospecific route to unsymmetrical 2,3-disubstituted indoles, Chem. Commun., 53, 4203-4206.

[4] He, Y.H.; Wang, Y.Q.; Gao, J.; Zeng, L.; Li, S.S.; Wang, W.; Zheng, X.H.; Zhang, S.Y.; Gu, L.J.;*  Li, G.P.*  (2018)  GanCatalytic, metal-free alkylheteroarylation of  alkenes via distal heteroaryl ipso-migration, Chem. Commun., 54, 7499-7502.

[5] Zhang, X.W.; He, Y.H.; Li, J.; Wang, R.; Gu, L.;* Li, G.P.*  (2019) CO₂/photoredox-cocatalyzed tandem oxidative cyclization of α‑Bromo Ketones and amines to construct substituted oxazoles,  J. Org. Chem., 84, 8225−8231.

[6] He, Y.H.; Zeng, L.; Li, M.; Gu, L.J.;* Zhang, S.Y.; Li, G.P.* (2022)  Electrochemical Oxidative C–C Bond Cleavage of Ketones for C–N Bond Formation: A Route to Amides J. Org. Chem., 2022, 87, 12622−12631.

[7]  Zhao, Z.H.; He, Y.H.; Li, M.; Xu, J.Z.; Li, X.G.;*  Zhang, L.Z.; Gu, L.J.*  An electrochemical multicomponent [3 + 1 + 1] annulations to synthesize polysubstituted 1,2,4-triazoles, Terahedron, 2021, 87:132111.

[8] Zhao, Z.H.; Yan, H.Y.; Zhou, Y.Q.; Xue, W.; Gu, L.J.;* Zhang, S.Y.  (2024) Electrocatalytic Multicomponent Cascade Cross-Coupling for the Synthesis of Chalcogenosulfonates. Chin. J. Chem, 42: 2049-2055.

[9] Zeng, L.; Li, J.; Gao, J.; Huang, X.H.; Wang, W.; Zheng, X.H.; Gu, L.J.;* Li, G.P.; Zhang, S.Y.; He, Y.H.* (2020) An Electrochemical Oxidative Multicomponent Cascade Annulation of Ketones and Amines used to Produce Imidazoles. Green Chem.  22, 3416‒3420.

[10] Zhang, C.; Zhou, Y.Q .; Zhao, Z.H. ; Xue, W.; Gu, L.J.* (2022)  An Electrocatalytic Three-Component Reaction for the Synthesis of Phosphoroselenoates. Chem. Commun. 58, 13951‒13954.