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Wei Xue PhD

AddTime: 2024-07-23     Hits: 82

Xue Wei PhD

Professor of Science in Chemistry

Doctoral Supervisor

State Key Laboratory of Green Pesticides (link to the main page of the lab)


Contact details

Room 201, Science Building, Center for Research and Development of Fine Chemicals, Guizhou University,East Campus, Guizhou University, China

Phone 0851-88292090

Email wxue@gzu.edu.cn


Qualifications

BSc – Guizhou Normal University, Guiyang, Guizhou, China 1992

PhD – Guizhou University, Guiyang, Guizhou, China 2011

MSc – Guizhou University, Guiyang, Guizhou, China 2005


Selected Positions held

2012-present Professor – Guizhou University, China

2007-2012 Associate Professor – Guizhou University, China

2005-2007 Lecturer – Guizhou University, China



Profile

Professor Xue Wei is an esteemed scholar in the domain of fine chemical engineering, with a distinguished reputation for his contributions to green drug design and synthesis, as well as the innovative development of new pesticides from natural sources. His pioneering work has significantly propelled the field of pesticide science forward, enhancing both the efficacy and safety of pesticides while simultaneously promoting environmental sustainability and ecological balance. Steering the projects of pivotal projects funded by the National Natural Science Foundation of China, Professor Xue has taken the lead in research initiatives that delve into the intricate design, synthesis, and biological activity of chalcone and myricetin derivatives. These projects not only exemplify his leadership in scientific inquiry but also underscore his commitment to fostering advancements that align with environmental and health-conscious agendas.

Selected research grants

  1. National Natural Science Foundation of China (32072446)

  2. National Natural Science Foundation of China (21867003)


Selected recent publications(*corresponding authors)

  1. Miaohe Zhang, Shuang Fenga, Junrong Song, Xianghui Ruan,* Wei Xue,* Formononetin derivatives containing benzyl piperidine: a brand new, highly efficient inhibitor targeting Xanthomonas spp. Journal of Advanced Research, 2025,73,133-146.

  2. Tianyu Deng, Hui Xin, Xingping Luo, Qing Zhou, Yuhong Wang, Chunmei Hu, Hong Fu, Wei Xue,* Antifungal activity of chalcone derivatives containing 1,2,3,4-tetrahydroquinoline and studies on them as potential SDH inhibitors,Pest Management Science, 2025, 81, 1251-1260.

  3. Hui Xin, Yi Liu, Tianyu Deng, Hong Fu, Yuhong Wang, Chunmei Hu, Haotao Pu, Xingping Luo, Wei Xue*, Discovery of potential fungicidal candidates: Chalcone derivatives containing piperidine and thiourea fragments,Journal of Agricultural and Food Chemistry, 2025,73, 17, 10101-10109.

  4. Jiao Tian, Yi Liu, Hui Xin, Chunmei Hu, Jieyu Li, Yuhong Wang, Xingping Luo, Yujiao Qiu, Wei Xue, * Discovery of Novel Flavonoid Derivatives Containing Benzothiazole as Potential Antifungal Agents, Pest Management Science, 2025,81,4,2288-2299.

  5. Piao Mao, Li Xing, Bangcan He, Tianyu Deng, Yishan Qin, Yuzhi Hu, Youshan An, Wei Xue,*Antiviral activity evaluation and action mechanism of chalcone derivatives containing phenoxypyridine, Molecular Diversity, 2025, 29, 695-709.

  6. Bangcan He, Yuzhi Hu, Yishan Qin, Yufang Zhang, Xingping Luo, Zhenchao Wang,* Wei Xue,* Design, synthesis and antiviral activity of indole derivatives containing quinoline moiety, Molecular Diversity, 2025, 29, 1091-1107.

  7. Yi Liu, Hui Xin, Yuhong Wang, Qing Zhou, Jiao Tian, Chunmei Hu, Xingping Luo, Haotao Pu, Wei Xue,* Flavonol derivatives containing piperazine and quinoxaline fragments: synthesis and antifungal activity, Molecular Diversity,2025, 29, 2193-2208.

  8. Tianyu Deng, Kaini Meng, Youshan An, Hong Fu, Yuhong Wang, Hongqian Zou, Da Liu,* Wei Xue,* Bioactivity ofchalcone derivatives containing 1,2,3,4-tetrahydroquinoline against Xanthomonas citri pv.mangiferae, Pest Management Science, 2025, 81(9), 5813-5826.

  9. Miaohe Zhang; Shuang Feng; Junyong Song; Wei Xue, Development and action mechanism of a series of novel antibacterial compounds based on natural product formononetin for controlling crop diseases, Journal of Agricultural and Food Chemistry, 2025, 73, 18680-18690.

  10. Youshan An, Kaini Meng, Tianyu Deng, Hong Fu, Hongqian Zou, Yujiao Qiu, Haotao Pu, Yufang Zhang, Mingman Sun, Wei Xue,* Design, synthesis and anti-TMV activity studies of myricetin derivatives containing oxime-ether triazole, Journal of Molecular Structure, 2025, 1348, 143431.

  11. Nian Zhang, Wei Zeng, Qing Zhou, Zhiling Sun, Kaini Meng, Yishan Qin, Yuzhi Hu, Wei Xue,* Design, synthesis and bioactivity of chalcone derivatives containing benzoxazole,Arabian Journal of Chemistry, 2024, 17, 105368.

  12. Chunmei Yuan, Tao Zhang, Jiao Tian, Tianyu Deng, Hui Xin, Yi Liu, Yufang Zhang, Wei Xue,* A potential antifungal agent: insight into the antifungal mechanism a gainst Phomopsis sp, Arabian Journal of Chemistry, 2024, 17, 105480.

  13. Piao Mao, Tianyu Deng, Jiao Tian, Yi Liu, Hui Xin, Youshan An, Yuzhi Hu, Yishan Qin, Wei Xue,* Design, synthesis, and antifungal activities of chalcone derivatives containing piperidine and sulfonamide moiety, Journal of Saudi Chemical Society，2024, 28, 101791.

  14. Chenyu Gong, Yuanxiang Zhou, Qing Zhou, Kaini Meng, Zhiling Sun, Wei Zeng, Youshan An, Yishan Qin, Xingping Luo, Wei Xue,* Novel flavonoid derivatives containing 1,2,4-triazolo[4,3-a]pyridine as potential antifungal agents: design, synthesis, and biological evaluation, Journal of Saudi Chemical Society, 2024, 28, 101797.

  15. Yuanxiang Zhou, Zhiling Sun, Qing Zhou, Wei Zeng, Miaohe Zhang, Shuang Feng, Wei Xue,* Novel flavonol derivatives containing benzoxazole as potential antiviral agents: design, synthesis, and biological evaluation, Molecular Diversity, 2024,28,3919-3935.

  16. Bangcan He,Yuzhi Hu, Piao Mao, Tianyu Deng, Yuhong Wang, Xingping Luo, Hongqian Zou, Zhenchao Wang, Wei Xue,*Design, Synthesis and Antifungal Activity of Indole Derivatives Containing 1,3,4-oxadiazole, Arabian Journal of Chemistry, 2024,17, 105758.

  17. Bangcan He, Yuzhi Hu, Li Xing, Yishan Qing, Kaini Meng, Wei Zeng, Zhiling Shun, Zhenchao Wang,* Wei Xue,* Antibacterial and antiviral activities of indole derivatives containing 1,3,4-thiadiazole, Journal of Agricultural and Food Chemistry, 2024, 72, 18, 10227-10235.

  18. Zhiling Sun, Wei Zeng, Qing Zhou, Yujiao Qiu, Yuzhi Hu, Hong Fu, Hongqian Zou, Yuhong Wang, Chunmei Hu, Jieyu Li, Wei Xue, Design, synthesis and antiviral activity of flavonol derivatives containing piperidine sulfonamide,Arabian Journal of Chemistry, 2024, 17, 105944.

  19. Yi Liu, Jiao Tian, Wei Zeng, Yuhong Wang, Chunmei Hu, Xingping Luo, Yujiao Qiu, Haotao Pu, Yongjun Wu, Wei Xue*, Antifungal activity of novel flavonol derivatives containing quinoxaline, Journal of Agricultural and Food Chemistry, 2024, 72, 43, 23766-23775.

  20. Wei Zeng, Zhiling Sun, Yi Liu, Qing Zhou, Yufang Zhang, Yujiao Qiu, Hong Fu, Hongqian Zou, Haotao Pu, Wei Xue*Design and research of new virulence factor inhibitors for plant bacterial disease control, Arabian Journal of Chemistry, 2024, 17(12), 106042.

  21. Youshan An, Hongqian Zou, Qing Zhou, Tianyu Deng, Jiao Tian, Yujiao Qiu, Wei Xue, Design, synthesis and biological activity studies of myricetin derivatives containing diisopropanolamine structure" Journal of Agricultural and Food Chemistry, 2024, 72, 25034-25044.

  22. Kaini Meng, Tianyu Deng, Min Liub, Haotao Pu, Yufang Zhang, Hongqian Zou, Yunping Xing, Wei Xue*，Novel flavonoid derivatives containing 1,2,4-triazole Schiff bases as potential antifungal agents: design, synthesis, and biological evaluation,Bioorganic Chemistry, 2024, 153, 107965.

  23. Shuang Feng, Miaohe Zhang, Junrong Song, Xianghui Ruan, Xue, Wei, Discovery of Highly Effective Antibacterial Agents based on Chalcone Scaffold against Plant Pathogens, Journal of Agricultural and Food Chemistry,2024, 72, 27808-27817.

  24. Wenliang Zhan, Ran Zhou, Piao Mao, Chunmei Yuan, Tao Zhang, Yi Liu, Jiao Tian, Hua Wang*, Wei Xue,* Synthesis, antifungal activity and mechanism of Action of novel chalcone derivatives containing 1,2,4-triazolo[3,4-b] -1,3,4-thiadiazole, Molecular Diversity, 2024, 28, 461-474.

  25. Qifan Wang, Li Xing, Yuanquan Zhang, Chenyu Gong, Yuanxiang Zhou, Nian Zhang, Bangchan He and Wei Xue*, Antiviral activity evaluation and action mechanism of myricetin derivatives containing thioether quinoline moiety, Molecular Diversity, 2024, 28, 1039-1055.


Selected patents

  1. Xue Wei, Shichun Jiang, Ziyou Huai, Xu Tang, Yinjiu Huang, Liwei Liu, Mei Chen, Jun He, Shijun Su, "4-(N-Methyl)aminopiperidine Myricetin Derivative Containing Dithiocarbamate, Preparation Method and Application", US Patent: US 12,043,617 B2, Application Date: December 29, 2019, Grant Date: July 23, 2024.

  2. Xue Wei, Shichun Jiang, Ying Chen, Shijun Su, Jun He, Mei Chen, Meimei Jin, Ming He, Jun Wang, "Sulfonamide-Containing 4-(N-Methyl)aminopiperidine Myricetin Derivatives, Preparation Method and Application", US Patent: US 12,063,930 B2, Application Date: December 26, 2019, Grant Date: August 20, 2024.

  3. Xue Wei, Nan Sun, Sizhu Pan, Chenyu Gong, Yuanxiang Zhou, Tianyu Deng, Youshan An, Kaini Meng, Ping Lu, "Chalcone Compounds Containing Thiazole Oxime Ether and Their Preparation Method and Application", Chinese Invention Patent: ZL 202310074830.8, Application Date: February 7, 2023, Grant Date: May 24, 2024.

  4. Xue Wei, Shuai Chen, Sizhu Pan, Wei Zeng, Jiao Tian, Yi Liu, Zhiling Sun, Ping Lu, "Chalcone Derivatives Containing Pyridazine and Their Preparation Method and Application", Chinese Invention Patent: ZL 202310072400.2, Application Date: February 7, 2023, Grant Date: September 3, 2024.

  5. Xue Wei, Hu Die,  SizhuPan, Sun Nan, Zhang Nian,  YuanxiangZhou, Zeng Wei, Xin Hui, "An Indole-Containing Chalcone Derivative, Its Preparation Method and Application", Chinese Invention Patent: ZL 202310150947.X, Application Date: February 22, 2023, Grant Date: October 18, 2024

  6. Xue Wei,  QifanWang,  SizhuPan, YuanquanZhang , Xing Li,  YuanxiangZhou,  ChenyuGong,  BangcanHe, Zhang Nian, Lu Ping, "A Class of Myricetin Compounds Containing 1,2,4-Triazolo[3,4-b]-1,3,4-thiadiazole and Their Preparation Method", Chinese Invention Patent: ZL 202211455216.8, Application Date: November 21, 2022, Grant Date: November 5, 2024