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Wen-Xin Lv PhD

AddTime: 2024-07-22     Hits: 10

Professor of Pesticide Science

Doctoral Supervisor

State Key Laboratory of Green Pesticides 

Contact details

Room 202-3, Block D, East Campus, Guizhou University

Email wxlv@gzu.edu.cn

Phone +86 15521330178

Qualifications

BSc – Jiangxi University of Traditional Chinese Medicine, China 2014

PhD – Sun Yat-Sen University, China 2019

Positions held

2019-2020  Associate Researcher– Sun Yat-Sen University, China

2020 -2023 Postdoc – Nanyang Technological University, Singapore

2023-present  Professor – Guizhou University, China

Profile

Wenxin Lv is a winner of the National Outstanding Youth Science Fund (Overseas) Project. She has been engaged in basic and applied research on organic synthesis methodology and drug molecular design for a long time, including glycochemistry, boron chemistry, fluorine chemistry, N-heterocyclic carbene catalysis, free radical reaction, organic small molecule catalysis and drug molecular synthesis, etc. She has made important research achievements in development of new organic synthesis methods. A series of new methods for the efficient construction of valuable small organic molecules have been developed. Her research mainly innovated and integrated relevant advances in chemistry, biology and other fields, and focused on creation of novel sugar pesticide molecules, solving scientific problems such as accurate modification and rapid construction of complex pesticide active molecules with saccharide fragments, and realizing the function improvement or activity change of saccharide pesticide molecules. To develop high efficiency sugar-based novel pesticide and its green synthetic production technology. She has published more than 20 papers in international journals including Chem, Angew. Chem. Int. Ed., ACS Catal., Chem. Sci., and so on.

Selected recent publications (*corresponding author)

Lv, W.-X.; Chen, H.; Zhang, X.; Ho, C. C.; Liu, Y.; Wu, S.; Wang, H.; Jin, Z.; Chi, Y. R.* Programmable Selective Acylation of Saccharides Mediated by Carbene and Boronic Acid. Chem 2022, 8, 1518–1534.

Lv, W.-X.; Li, Y.; Cai, Y.-H.; Tan, D.-H.; Li, Z.; Li, J.-L.; Li, Q.; Wang, H*. Hypervalent Iodine-Mediated β-Difluoroalkylboron Synthesis via An Unusual 1,2-Hydrogen Shift Enabled by Boron Substitution. Chem. Sci., 2022, 13, 2981-2984.

Lv, W.-X.; Li, Q.; Li, J.-L.; Li, Z.; Lin, E; Tan, D.-H.; Cai, Y.-H.; Fan, W.-X.; Wang, H*. gem-Difluorination of Alkenyl MIDA Boronates: Synthesis of α- and β-Difluorinated Alkylborons. Angew. Chem. Int. Ed. 2018, 57, 16544-16548.

Lv, W.-X.; Li, Z.; Lin, E; Li, J.-L.; Tan, D.-H.; Cai, Y.-H.; Li, Q.; Wang, H*. Regio- and Diastereoselective Synthesis of Cyclohexadienylborons via Intermolecular Diels-Alder Reaction of Alkenyl MIDA Boronates with 2-Pyrones. Chem. Eur. J. 2019, 25, 4058-4061.

Lv, W.-X.; Zeng, Y.-F.; Li, Q.; Chen, Y.; Tan, D.-H.; Yang, L.; Wang, H*. Oxidative Difunctionalization of Alkenyl MIDA Boronates: A Versatile Platform for Halogenated and Trifluoromethylated α-Boryl Ketone. Angew. Chem. Int. Ed. 2016, 55, 10069 –10073.

Lv, W.-X.; Zeng, Y.-F.; Zhang, S.-S.; Li, Q.; Wang, H*. Mild Mn(OAc)3‑Mediated Aerobic Oxidative Decarboxylative Coupling of Arylboronic Acids and Arylpropiolic Acids: Direct Access to Diaryl 1,2-Diketones. Org. Lett. 2015, 17, 2972−2975.