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Run-Jiang Song PhD

AddTime: 2024-07-22     Hits: 123

Curriculum Vitae


Name: Runjiang Song, PhD

Title: Professor of GZU

Contact: songrj@gzu.edu.cn

ORCID iD: 0000-0003-2502-778X

Lab website: https://www.x-mol.com/groups/Song_green_pesticide

Education: (2022) PhD. Nanyang Technological University, Singapore.

           (2016) BSc. East China University of Science and Technology, Shanghai, China.

Research interests and achievements: Runjiang Song’s research focuses on the development of green pesticides, including the design of new agrochemical structures derived from natural products, bioactivity screening, and the employment of advanced molecular biology techniques to elucidate their mechanisms of action. He has published 37 papers in internationally renowned journals such as Science Bulletin, Nature Synthesis, Nature Communications, Engineering, Research, Angewandte Chemie International Edition and Advanced Science. He supervised students in developing the novel mesoionic insecticide "ezuochongmiding" whose related patent was transferred to Qingdao KingAgroot CropScience Co., Ltd. for industrial development for 16 million yuan. He has received the First Class Prize of the Guizhou Provincial Scientific and Technological Progress Award and the Journal of Agricultural and Food Chemistry Research Article of the Year Award 2024. He serves as a young editorial board member for Agriculture Communications, Chinese Journal of Applied Entomology, and Journal of Plant Protection.

Research funding (selected):

  1. National Key Research and Development Program of China (No. 2023YFD1400405)

  2. General Program of National Natural Science Foundation of China (No. 32272590)

  3. Youth Fund of the National Natural Science Foundation of China (No. 32302388)

Awards:

  1. Young Scholar of “Cheung Kong Scholars Programme” (2024)

  2. Journal of Agricultural and Food Chemistry Research Article of the Year Award (2024)

  3. First Class Prize of Guizhou Scientific and Technological Progress Award (2023)

Publication (selected):

  1. Limin Yin, Xiangyang Li, Chunni Zhao, Runjiang Song*, Baoan Song*. CGMMV capsid protein hijacks host pro-viral factors to generate condensates and remodel photosynthesis: strategic antiviral protocol. Science Bulletin. 2025. (https://doi.org/10.1016/j.scib.2025.05.012).

  1. Ningning Zan, Jiao Li, Jiahui Yao, Shang Wu, Jianzhuan Li, Feifei Chen, Baoan Song*, Runjiang Song*. Rational design of phytovirucide inhibiting nucleocapsid protein aggregation in tomato spotted wilt virus. Nature Communications. 2025, 16, 2034. (https://doi.org/10.1038/s41467-025-57281-z).

  1. Xiaoyi Wang, Weijia Yang, Shang Wu, Fangru Jin, Zhongjie Shen, Xiangyang Li*, Yonggui Robin Chi, Baoan Song, and Runjiang Song*. Carbene-Catalyzed Phthalide Ether Functionalization for Discovering Chiral Phytovirucide that Specifically Targets Viral Nia Protein to Inhibit Proliferation. Research. 2025, 8, 0637. (https://spj.science.org/doi/abs/10.34133/research.0637).

  1. Runjiang Song, Yuping Zhang, Ping Lu, Jian Wu, Qing X. Li*, and Baoan Song*. Status and Perspective on Green Pesticide Utilizations and Food Security. Annual Review of Food Science and Technology. 2024, 15, 473-493. (https://doi.org/10.1146/annurev-food-072023-034519).

This review gives a short explanation of what "green pesticides" are and talks about their importance, how they are currently registered and used in China, the EU, and the US. Following this, we do a thorough study of how the newest green pesticides affect communities and the environment. Finally, we look at the possible dangers of eating foods that contain green poisons, as well as the risks of long-term toxicity and cancer.

  1. Chunle Wei, Chunni Zhao, Jiao Li, Chunyi Li, Baoan Song, Runjiang Song*. Innovative Arylimidazole-Fused Phytovirucides via Carbene-Catalyzed [3+4] Cycloaddition: Locking Viral Cell-To-Cell Movement by Out-Competing Virus Capsid-Host Interactions. Advanced Science, 2024, 11(19): 2309343. (https://doi.org/10.1002/advs.202309343).

A highly efficient and selective carbene-catalyzed [3+4] cycloaddition is developed in this study, which allows the one-step synthesis of a series of optically-enriched imidazo[1,2-α][1,4]diazepins. Compound -3j (S) is screened out as a potential phytovirucide that locks cell-to-cell movement of potato virus Y by out-competing virus capsid-host interactions at the molecular level.

  1. Awei Zhang, Haizhen Zhang, Ronghua Wang, Hongfu He, Baoan Song*, Runjiang Song*. Bactericidal bissulfone B7 targets bacterial pyruvate kinase to impair bacterial biology and pathogenicity in plants. Science China Life Sciences, 2024, 67(2): 391−402. (https://doi.org/10.1007/s11427-023-2449-1).

This study identifies pyruvate kinase as a potential new target against rice bacterial leaf blight and offers insights into the molecular and mechanistic aspects underlying anti-Xoo strategies that target PYK.

  1. Runjiang Song, Shichao Ren*, Yonggui Robin Chi*. Carbene-and photocatalysis redefine arene acylation. Nature Synthesis, 2023, 2(11): 1009−1011. (https://doi.org/10.1038/s44160-023-00400-9).

  2. Hongxia Lu, Zhongjie Shen, Yujun Xu, Linjing Wu, Deyu Hu, Runjiang Song,* and Baoan Song*. Immune Mechanism of Ethylicin-Induced Resistance to Xanthomonas oryzae pv. oryzae in Rice. Journal of Agricultural and Food Chemistry, 2023, 71(1), 288–299. (https://doi.org/10.1021/acs.jafc.2c07385).

This research identifies OsCPK24 as a key mediator in rice resistance to Xoo, paving the way for the development of new bactericides leveraging OsCPK24. (Winner of the AGRO Division Research Article of the Year Award)

  1. Runjiang Song, Yongtao Xie,* Zhichao Jin and Yonggui Robin Chi* Carbene-Catalyzed Asymmetric Construction of Atropisomers. Angewandte Chemie-International Edition, 2021, 60(50), 26026–26037. (https://doi.org/10.1002/anie.202108630).