Zhi-Bing Wu PhD

Professor of Plant Protection

Master's Supervisor

State Key Laboratory of Green Pesticides

Contact details

D-113, East Campus, Guizhou University

Email zbwu@gzu.edu.cn

Phones +86-851-8829-2090; +86 186 8515 8173

Qualifications

BSc – Jiangsu Ocean University, China 2005

MSc – Sichuan University, China 2008

PhD – Guizhou University, China 2012

Positions held

2010 – 2012 Lecturer – Guizhou University, China

2013 – 2021 Associate Professor – Guizhou University, China

2022 – present Professor - Guizhou University, China

Profile

Zhi Bing Wu is a senior pesticide scientist of Guizhou University. His research mainly focuses on design and synthesis of small molecules of pesticides and action mechanisms of highly active molecules. He has been the principal investigator of four National Natural Science Foundation of China grants and three Guizhou provincial grants. He has participated in one Ministry of Science and Technology research program and several provincial and ministerial research projects. Wu has published more than 40 scientific papers in national and international journals, such as Chinese Chemical Letters, Journal of Heterocyclic Chemistry, and Science China Chemistry. He also holds six national invention patents.

Selected recent publications (*corresponding authors)

Wen, F.L.; Liu, Z.X.; Zheng, Y.; Song, D.D.; Chen, K.; Wu, Z.B.* (2024) Repairing Host Damage Caused by TMV Stress: Design, Synthesis and Mechanism Study of Novel Oxadiazole and Arylhydrazone Derivatives. J Agric Food Chem https://doi.org/10.1021/acs.jafc.3c09463

Zhang, Y.Q.; Wang, X.; Shi, H.B.; Siddique, F.; Xian, J.X.; Song, A.T.; Wang, B.L.; Wu, Z.B.*, Cui, Z. N* (2024) Design and Synthesis of Mandelic Acid Derivatives for Suppression of Virulence via T3SS against Citrus Canker. J Agric Food Chem 72: 9611-9620.

Song, D.D.; Wen, R.; Chen, K.; Wen, F.L.; Xing, D.*; Wu, Z.B.* (2024) Application of thifluzamide to stem rot in peppers: Infection and control mechanisms of sclerotium rolfsii. Pestic Biochem Phys 200: 105846.

Chen, X.C.; Niu, X.; Li, L.J.; Chen, K.; Song, D.D.; Chen, B.^*; Yang, S.^*; Wu, Z.B.^* (2024) Design, Synthesis and Target Identification of Novel Phenylalanine Derivatives by Drug Affinity Responsive Target Stability (DARTS) in Xanthomonas oryzae pv. oryzae. J Agric Food Chem 72: 3436-3444.

Guo, Q.Q.; Li, Y.Z.; Shi, H.B.; Yi, A.Y.; Xu, X.L.; Wang, H.H.; Deng, X.; Wu, Z.B.*; Cui Z.N.* (2023) Novel mandelic acid derivatives suppress virulence of Ralstonia solanacearum via type III secretion system. Pest Manag Sci 79: 4626-4634.

Hou, S.T.; Shi, H.B.; Zhang, H.; Wu, Z.B.*; Hu, D.Y. (2023) Synthesis, Antifungal Evaluation, 3D-QSAR and Preliminarily Mechanism Study of Novel Chiral Mandelic Acid Derivatives. J Agric Food Chem 71(20), 7631-7641.

Zhang, C.Z.; Zhao, C.L;  Zheng, H.L.; Li, L.J.; Zheng, Y.; Wu, Z.B.* (2023) Design, Synthesis and Study of the Dual Action Mode of Novel N-Thienyl-1,5-disubstituted-4-pyrazole Carboxamides against Nigrospora oryzae. J Agric Food Chem 71: 7210-7220.

Zhang, C.Z.; Yang, J. X; Zhao, C.L; Li, L.J.; Wu, Z.B.* (2023) Potential Fungicide Candidates: Dual Action Mode Study of Novel Pyrazole-4-Carboxamides against Gibberella zeae. J Agric Food Chem 71: 1862-1872.

Zheng, H.L.; Wen, F.L.; Zhang, C.Z.; Luo, R.; Wu, Z.B.* (2023) Novel 1,3,4-thiadiazole Derivatives: Synthesis, Antiviral Bioassay, and Regulation the Photosynthetic Pathway of Tobacco against TMV Infection. Int J Mol Sci 24: 8881.

Shi, H.B.; Li, L.J.; Song, D.D.; Zheng, Y.; Wu, Z.B.* (2023) In vitro/vivo antifungal activity study of novel mandelic acid derivatives as potential fungicides against Thanatephorus cucumeris. Arab J Chem 16: 104884.

Yang, J. X; Xie, D.W.; Zhang, C.Z.; Zhao, C.L.;  Wu, Z.B.*; Xue, W.* (2022) Synthesis, antifungal activity and in vitro mechanism of novel 1-substituted-5-trifluoromethyl-1H-pyrazole-4-carboxamide derivatives. Arab J Chem 15: 103987-103997.

Wu, Z.B.; Park, H.Y.; Xie, D.W.; Yang, J.X.; Hou, S.T.; Shahzad, N.; Kim, C.K.*; Yang, S.* (2021) Synthesis, biological evaluation and 3D-QSAR studies of N-(substituted pyridine-4-yl)-1-(substituted phenyl)-5-trifluoromethyl-1H-pyrazole-4-carboxamide derivatives as potential succinate dehydrogenase inhibitors. J Agric Food Chem 69: 1214-1223.

Wu, Z.B.*; Yang, W.Q.; Hou, S.T.; Xie, D.W.; Yang, J.X.; Liu, L.W.; Yang, S.* (2021) In vivo antiviral activity and disassembly mechanism of novel 1-phenyl-5-amine-4-pyrazole thioether derivatives against Tobacco mosaic virus. Pestic Biochem Phys 173: 104771.

Yang, G.Q.; Zheng, H.L.; Shao, W.B.; Liu, L. W.; Wu, Z.B.* (2021) Study of the in vivo antiviral activity against TMV treated with novel 1-(t-butyl)-5-amino-4-pyrazole derivatives containing a 1,3,4-oxadiazole sulfide moiety. Pestic Biochem Phys 171: 104740.

Zhou, X.; Ye, Y.Q.; Liu, S.S.; Shao, W.B.; Liu, L.W.; Yang, S.*; Wu, Z.B.* (2021) Design, synthesis and anti-TMV activity of novel α-aminophosphonate derivatives containing a chalcone moiety that induce resistance against plant disease and target the TMV coat protein. Pestic Biochem Phys 72: 104749.