Xing-Xing Wu PhD

Professor of Pesticide Chemistry

Doctoral Supervisor

State Key Laboratory of Green Pesticides 

https://orcid.org/0000-0002-6281-243X

Contact details

336 Building D, Center for Research and Development of Fine Chemicals，East Campus, Guizhou University

Email wuxx@gzu.edu.cn

Phone 13673292839

Qualifications

PhD - Nanyang Technological University, Singapore 2017

MSc - East China Normal University, 2013

BSc - East China Normal University 2010  

Positions held

2022.05-present   Professor, Guizhou University, China

2018.05-2022.02  Postdoctoral Research Fellow, University of Basel, Switzerland

2018.02-2018.05  Project Officer, Nanyang Technological University, Singapore

Profile

Xingxing Wu has been selected for the National Overseas High-Level Young Talents Program. He serves as the academic discipline leader at Guizhou University, and a youth editorial board member of the Journal of Pesticide Science. He was appointed as a Marie Curie scholar by the European Research Council. His research focuses on the development of green and efficient asymmetric catalytic synthesis methods. He has established a series of universal asymmetric preparation technology models, facilitating the efficient construction of various libraries of chiral compounds with pesticide activity. As the first author or corresponding author, he has published over 30 papers in high-impact journals such as Nature Catalysis, Chem, Angewandte Chemie International Edition, and Trends in Chemistry. Some of his achievements have been recognized with awards such as the 2023 Qingyuan Green Pesticide Outstanding Teacher Award, the Swiss Chemical Society-Helvetica 2^nd Prize (2023), and the 2017 China Scholarship Council's Outstanding Self-Financed Overseas Student Scholarship.

Selected recent publications (*corresponding authors)

Luo, Z., M. Liao, W. Li, S. Zhao, K. Tang, P. Zheng, Y. R. Chi, X. Zhang* and X. Wu* (2024). Ionic Hydrogen Bond-Assisted Catalytic Construction of Nitrogen Stereogenic Center via Formal Desymmetrization of Remote Diols. Angew. Chem. Int. Ed. 63: e202404979.

Liao, M., Y. Liu, H. Long, X. Lv, Z. Luo, F. Che, X. Wu* and Y. R. Chi* (2024) Enantioselective sulfinylation of alcohols and amines by condensation with sulfinates. Chem. doi: 10.1016/j.chempr.2024.02.016.

Lv, X., F. Su, H. Long, F. Lu, Y. Zeng, M. Liao, F. Che, X. Wu* and Y. R. Chi* (2024) Carbene Organic Catalytic Planar Enantioselective Macrolactonization. Nat. Commun. 15: 958.

Su, F., F. Lu, K. Tang, X. Lv, Z. Luo, F. Che, H. Long, X. Wu* and Y. R. Chi* (2023) Organocatalytic C-H Functionalization of Simple Alkanes. Angew. Chem. Int. Ed. 62: e202310072.

Su, F., J. Zou, X. Lv, F. Lu, Y. Long, K. Tang, B. Li, H. Chai, X. Wu* and Y. R. Chi* (2023) Carbene-Catalyzed Intermolecular Dehydrogenative Coupling of Aldehydes with C(sp³)-H Bonds. Angew. Chem. Int. Ed. 62: e202303388.

Long, H., S. Zhao, C. Jian, X. Wu, F. Lu, M. Liao, F. Che, X. Wu* and Y. R. Chi* (2024) Carbene-catalyzed Enantioselective Seleno-Michael Addition as Access to Antimicrobial Active Se-containing Heterocycles. Sci. China. Chem. doi: 10.1007/s11426-023-1909-5. 

Wu, X., R. Witzig, R. Beaud, C. Fischer, D. Häussinger, C. Sparr* (2021) Catalyst Control over Sixfold Stereogenicity. Nature Catal 4: 457−462.

Wang, H., X. Wu* and Y. R. Chi* (2022) Distal Difunctionalization of Aldehydes via the Triplet State of Breslow Intermediates. Chem Catal. 2: 3275–3277.

Tang, K., F. Su, S. Pan, F. Lu, Z. Luo, F. Che, X. Wu* and Y. R. Chi* (2024) Enones from Aldehydes and Alkenes by Carbene-catalyzed Dehydrogenated Couplings. Chin. Chem. Lett. doi: 10.1016/j.cclet.2024.109495.

Teng, K., Q. Liu, M. Zhang, H. Naz, X. Wu* and Y. R. Chi* (2024) Design, Enantioselective Synthesis of Chiral Pyranone Fused Indole Derivatives with Antibacterial Activities against Xanthomonas oryzae pv. oryzae for Protection of Rice. J. Agric. Food. Chem. 72: 4622–4629.

Wang, Y., Y. Liu, S. Zhao, Y. Long, X. Wu* (2023) Catalyst-controlled Stereoselective Carbon‒heteroatom Bond Formations by N-Heterocyclic Carbene (NHC) Organocatalysis. Org. Chem. Front.10: 4437–4458.

Wang, H., F. Su, Y. Wang, X. Wu* and Y. R. Chi* (2023) Direct coupling of inert C–H bonds in NHC organocatalysis. Org. Chem. Front. 10: 5291–5295.

Liu, Y., Y. Wang, X. Wu* and Y. R. Chi* (2022) Exploring Molecular Complexity by N-Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity. Chem. Record 22: e202200219.

Wu, X., Liu, Y., Jin, Z. Organocatalytic Dynamic Kinetic Resolution (Chapter 3) in Dynamic Kinetic Resolution (DKR) and Dynamic Kinetic Asymmetric Transformations (DYKAT) (Eds. J.-E. Bäckvall), 2022, Georg Thieme Verlag KG, Stuttgart, Germany. (Book chapter)

Wu, X., C. Sparr* (2022) Retrosynthetic polyketide disconnections for unnatural aromatics, Trends in Chem. 4: 367−370.

Wu, X., C. Sparr* (2022) Stereoselective Synthesis of Atropisomeric Acridinium Salts by the Catalyst-Controlled Cyclization of ortho-Quinone Methide Iminiums. Angew. Chem. Int. Ed. 61: e202201424.

Wu, X, L. Zhou, R. Maiti, C. Mou, L. Pan* and Y. R. Chi* (2019) Sulfinate and Carbene Co-catalyzed Rauhut-Currier Reaction for Enantioselective Access to Azepino[1,2-a]indoles. Angew. Chem. Int. Ed. 58: 477−481.

Wu, X., L. Hao, Y. Zhang, M. Rakesh, R. N. Reddi, S. Yang,* B. Song and Y. R. Chi* (2017) Construction of Fused Pyrrolidines and β-Lactones by Carbene-Catalyzed C−N, C−C, and C−O Bond Formations. Angew. Chem. Int. Ed. 56: 4201−4205.

Wu, X., Y. Zhang, Y. Wang, J. Ke, M. Jeret, R. N. Reddi, S. Yang, B. Song* and Y. R. Chi* (2017) Polyhalides as Efficient and Mild Oxidants for Oxidative Carbene Organocatalysis by Radical Processes. Angew. Chem. Int. Ed. 56: 2942−2946.

Wu, X., B. Liu, Y. Zhang, M. Jeret, H. Wang, P. Zheng, S. Yang, B. Song and Y. R. Chi* (2016) Enantioselective Nucleophilic β-Carbon-Atom Amination of Enals: Carbene-Catalyzed Formal [3+2] Reactions. Angew. Chem. Int. Ed. 55: 12280−12284.

Zhou, L.J., X. Wu, X. Yang, C. Mou, R. Song, S. Yu, H.  Chai, L.  Pan, Z. Jin and Y. R. Chi* (2020) Gold and Carbene Relay Catalytic Enantioselective Cycloisomerization/Cyclization Reactions of Ynamides and Enals. Angew. Chem. Int. Ed. 59: 1557−1561.