Li-Bo Zhang PhD

Professor of Biochemistry

Doctoral Supervisor

State Key Laboratory of Green Pesticides 

Contact details

227 Physics and Chemistry Building, East Campus, Guizhou University

Email: lbzhang@gzu.edu.cn

Phone :13765005126

Qualifications

BSc – Henan Normal University, China 2007

MSc – Jilin University, China 2009

PhD – University of South Carolina, USA 2020

Positions held

2009-2011 Research Assistant – National Institute of Biological Sciences, Beijing, China

2011-2015 Research Associate – Novo Nordisk Research Center China, Beijing, China  

2020-2023 Postdoc – University of California (Davis), USA

2023 – present Professor – Guizhou University, China

Profile

Libo Zhang’s research focuses on the design and synthesis of oligosaccharides, peptides, and their assemblies for green pesticide discovery using principles and methods of enzymatic engineering, protein and material assembly, molecular biology and chemistry. In 2022, he was supported by the National High-Level Youth Talents Overseas Excellent Young Program. He has served on editorial board of Journal of Plant Protection and review editor of Frontiers in Chemical Biology since 2023.  He has published over 20 research papers in journals such as Bioresour. Technol., Mater. Sci. Eng. C, ACS Sustain. Chem. Eng., and Biomacromolecules.

Selected recent publications (*corresponding author)

Hai Yu, Libo Zhang (co-first), Xiaohong Yang, Yuanyuan Bai, Xi Chen*. Process Engineering and Glycosyltransferase Improvement for Short Route Chemoenzymatic Total Synthesis of GM1 Gangliosides. Chemistry–A European Journal, 2023, e202300005

Libo Zhang, Yanhong Li, Riyao Li, Xiaohong Yang, Zimin Zheng, Jingxin Fu, Hai Yu, and Xi Chen*. Glycoprotein in vitro N-Glycan Processing Using Enzymes Expressed in E. coli. Molecules, 2023, 28(6), 2753

Yihua Ren, Libo Zhang (co-first), Tao Sun, Yingwu Yin and Qian Wang*. Enzyme Immobilization on Delignified Bamboo Scaffold as Green Hierarchical Bioreactor. ACS Sustainable Chemistry & Engineering, 2022, 10, 19, 6244–6254 (Cover feature)

Libo Zhang and Qian Wang*. Harnessing P450 enzyme for biotechnology and synthetic biology. Chembiochem, 2021, 23 (3), e202100439 (Cover feature, Top 10 most-cited papers)

Libo Zhang, Dumei Ma (co-first), Yingwu Yin, Qian Wang*. Using small molecules to enhance P450 OleT enzyme activity in situ. Chemistry-A European journal, 2021,27(35), 8940-8945 (Cover feature)

Libo Zhang, Olivia M. Manley, Dumei Ma, Yingwu Yin, Thomas M. Makris, Qian Wang*. Enhanced P450 OleTSA catalysis promoted by glucose oxidase-based H2O2 production from abundant sugars. Bioresource technology, 2020, 311, 123538

Libo Zhang, Andrew Beatty, Lin Lu, Akrm Abdalrahman, Thomas Makris, Guiren Wang and Qian Wang*. Microfluidic-assisted polymer-protein assembly to fabricate homogeneous functional nanoparticles. Materials Science and Engineering C, 2020, 111, 110768

Libo Zhang, Yanmei Xu, Thomas M. Makris, Qian Wang*. Enhanced arylamine N-oxygenase activity of polymer-enzyme assemblies by facilitating electron-transferring efficiency, Biomacromolecules, 2018, 19, 918–925