吴剑教授简历

个人简介

吴剑，博士，1981年12月生，教授，博士生导师，入选国家级高层次人才、省部级青年人才、贵州省“重点联系省管专家”等。2010年12月在贵州大学获得农药学博士学位，随后留校从事教学科研工作。兼任中国化工学会第41届理事、中国化工学会第九届农药专委会委员、中国生物工程学会生物农业分会委员、《现代农药》副主编、《农药学学报》青年编委、国际期刊BMC Chemistry 编委。在国内外主要学术会议上作邀请报告20余次。参与出版专著及教材6部。

聚焦我国绿色农药缺乏原创性分子结构、清洁化生产技术短缺等科学问题和技术需求。开展基于天然产物、含氟杂环为主导的绿色农药的创制研究工作，发现10余个高活性先导及1个候选农药，申请国家发明专利20余项（获14项授权），其中“一种醚类化合物在促进植物生长方面的应用（ZL 2018110941705）”的专利以1000万元转让给鹤壁全丰生物科技有限公司进行产业化开发。迄今为止，作为第一/通讯作者在Angew. Chem. Int. Ed，Green Chemistry，Journal of Agricultural.and food Chemistry, Food and Energy Security等发表SCI论文60余篇。获中国石油和化学工业联合会优秀出版物一等奖、国家教育教学成果二等奖、贵州省教育教学成果特等奖、贵州省“最美科技工作者”等荣誉称号。

工作经历

教育经历

学术兼职

教学工作

本科生课程：

1. 农药化学（参讲）

2. 有机化学1-1（主讲）

3. 科研素质创新能力培养1（主讲）

4. 新农药发现前沿讲座（主讲）

5. 有机化学强基课程（参讲）

6. 科技论文检索与写作（主讲）

研究生课程：

1. 农药学（主讲）

2. 科技文献检索与论文写作（主讲）

  研究方向

1. 绿色农药的设计、合成及构效关系研究；

2. 有机合成；

3. 有机功能分子的合成研究；

4. 活性分子的作用机制。

代表性科研项目

1. 国家级领军人才项目，2022-01-01 ~ 2024-01-01

2. 国家自然科学基金委，新型酰腙类抗植物病毒衍生物的设计、合成及作用机制研究（32072445），2021-01-01 ~ 2024-12-31

3. 国家自然科学基金委，含三氟甲基吡啶杀虫化合物的结构多样性衍生与作用机制初探（21762012），2018-01-01 ~ 2021-12-01

4. 国家自然科学基金委，含氟取代(亚)磺酰基杂环衍生物的设计合成与生物活性研究(21562012),2016-01-01 ~ 2019-12-01

5. 国家自然科学基金委，新型含喹唑啉结构的吡唑酰胺衍生物的设计、合成及生物活性研究(21302025)2014-01-01 ~ 2016-12-01

6. 国家自然科学基金委，新型含酰腙结构吡唑酰胺衍生物的设计合成及杀虫活性研究(21162004)2012-01-01 ~ 2015-12-01

7. 国家科技部，高效低风险农药学科创新引智基地（111引智基地）, 2020-01-01 ~ 2025-12-31

8. 贵州省科技厅，新型杂环衍生物的设计合成及生物活性研究(黔科合人字（2015）15号，贵州省优秀青年科技人才项目),2015-09-22 ~ 2018-08-01

9. 贵州省科技厅，以天然产物阿魏酸为导向的新型抗植物病毒剂的创制研究(黔科合基础[2017]1402，重点项目)，2017-10-01 ~ 2021-10-01

10. 贵州省科技厅，新型吡唑酰胺类衍生物的合成及生物活性研究（黔科合J字[2014]2056号），2014-08-01~ 2017-08-01

11. 贵州省教育厅，新型含腙类结构的邻苯二甲酰胺衍生物的设计合成及杀虫活性研究（黔省专合字（2011）38号），2011-09-20 ~ 2014-09-20

12. 农业农村部种植业管理司，农药行业管理支撑服务--农药按毒性分类登记资料要求调研, 2022-05-18~2022-11-30

13. 农业农村部人才培养计划项目，2021-09-30 ~ 2022-04-30

14. 山东润丰，氯虫苯甲酰胺路线开发，2021-07-30~ 2021-08-31

15. 农业农村部种植业管理司，农业投入品综合管理服务, 2021-04-02 ~ 2021-11-30

16. 农业农村部种植业管理司，农药产业科技创新支撑服务, 2020-06-10 ~ 2020-09-3

17. 农业农村部种植业管理司，农药产品中有效成分测定通用分析方法—液相色谱法》体系建设：氨磺乐灵等8个农药品种液相色谱分析方法建立, 2019-11-15~ 2021-03-31

18. 农业农村部农药检定所，我国主要农药品种特性、理化等相关数据采集和分析，2018-08-01 ~2018-12-01

19. 农业农村部农药检定所，我国新农药创制研究及应用现状调研, 2015-02-01~ 2015-06-01中国农业出版社，中国农业百科文字资源委托建设, 2018-06-13 ~2019-06-01

20. 贵州大学，含杂环新型邻苯二甲酰胺类衍生物的设计合成及生物活性研究(贵大人基合字（2011）24号), 2012-01-01 ~ 2013-12-01

21. 贵州大学，ABA功能类似物合成及作用机制, 2020-11-01 ~ 2023-11-30.

代表性专著及论文

专著：

1. 吴  剑，李钟华. 《农药产业》，2019年，化学工业出版社；

2. 宋宝安，吴  剑. 《农药合成》，2017年，中国农业出版社；

3. 宋宝安，吴  剑. 《新杂环农药——除草剂》，2011年，化学工业出版社；

4. 王鸣华，宋宝安，吴  剑，等. 《农药立体化学》，2016年，化学工业出版社；

5. 宋宝安，金林红，等. 《新杂环农药——杀虫剂》，2010年，化学工业出版社（副主编）；

6. 宋宝安. 《新杂环农药——杀菌剂》，2009年，化学工业出版社（参编）；

论文：

1. Guoyong Luo, Zhijian Huang, Shitian Zhuo, Chengli Mou, Jian Wu *, Zhichao Jin, Yonggui Robin Chi*. Access to Cyclic beta-Amino Acids by Amine-Catalyzed Enantioselective Addition of the gamma-Carbon Atoms of alpha,beta-Unsaturated Imines to Enals[J].Angewandte Chemie-International Edition,2019, 58(48), 17189-17193.

2. Jian Wu,* Xianli Du, Juan Ma, Yuping Zhang, Qingcai Shi, Lijun Luo, Baoan Song,* Song Yang, Deyu Hu. Preparation of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media with α-cyclodextrin-SO₃H as a recyclable catalyst[J]. Green Chemistry, 2014, 16, 3210–3217.

3. Jiamiao Jin, Tingwei Shen, Liangzhen Shu, Yixian Huang, Youlin Deng, Benpeng Li, Zhichao Jin*, Xiangyang Li*, and Jian Wu*. Recent Achievements in Antiviral Agent Development for Plant Protection[J] Journal of Agricultural and Food Chemistry,2023, 71(3): 1291-1309.  

4. Dongyu Chen; Hui Huang; Yuanqin Huang; Weicheng Yang; Weili Shan; Gefei Hao*; Jian Wu*; Baoan Song. Toxicity Tests for Chemical Pesticide Registration: Requirement Differences among the United States, the European Union, Japan, and China?[J] Journal of Agricultural and Food Chemistry,2023, https://doi.org/10.1021/acs.jafc.3c00410 .  

5. Wei Zhang, Shengxin Guo , Lijiao Yu, Ya Wang, Yonggui Robin Chi,*Jian Wu*. Piperazine: Its role in the discovery of pesticides[J].Chinese Chemical Letters, 2023, doi:https://doi.org/10.1016/j.cclet.2022.108123.

6. Shengxin Guo; Feng He; Wei Zhang; Ya Wang; Lijiao Yu; Jian Wu*. Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight[J]. Food and Energy Security, 2023, doi:https://doi.org/10.1002/fes3.449.

7. Ya Wang, Shengxin Guo, Lijiao Yu, Wei Zhang, Zhenchao Wang,* Yonggui Robin Chi*, Jian Wu*. Hydrazone derivatives in agrochemical discovery and development [J]. Chinese Chemical Letters, 2023,doi:https://doi.org/10.1016/j.cclet.2023.108207

8. Wei Zhang, Shengxin Guo, Ya Wang, Yikun Wu, Lijiao Yu, Jian Wu*. Trifluoromethylpyridine piperazine derivatives: synthesis and anti-plant virus activity[J].Pest Management Science, 2023,doi:https://doi.org/10.1002/ps.7429

9. Zhiguo Zheng; Shunhong Chen; Panpan Wei; Shengxin Guo; Gang Yu; Jian Wu*. The proteomics and metabolomics studies of GZU001 on promoting the Merisis of maize (Zea mays L.) roots [J]. BMC Plant Biology, 2023, 23, 103.

10. Ping Sun, Yuanqin Huang, Xiaoyan Yang, Anjing Liao, Jian Wu*. The role of indole derivative in the growth of plants: A review[J]. Frontiers in Plant Science, 2023, 13: 1120613.  

11. Ali Dai, Zhiguo Zheng, Yuanqin Huang, Lijiao Yu, Zhenchao Wang *, Jian Wu*. Hydrazone modification of non-food natural product sclareolide as potentialagents for plant disease[J]. Heliyon, 2023, 8, e12391.

12. XinyuZhang, JinliZhang,JieChen,Banghua Zhou,JianZhang,Shunhong Chen,Jian Wu*,YaojiaJiang*. Modular synthesis of fluorinated 2H-thiophenes via [4 + 1] cyclization of enaminothiones[J]. Organic & Biomolecular Chemistry, 2023, 2023,21, 3345-3349

13. LijiaoYu,AliDai,WeiZhang,AnjingLiao,ShengxinGuo, Jian Wu* Spiro Derivatives in the Discovery of New Pesticides: A Research Review[J].Journal of Agricultural and Food Chemistry, 2022,70(35) , 10693-10707.

14. Lijiao Yu, Shengxin Guo, Ya Wang, Anjing Liao, Wei Zhang, Ping Sun, and Jian Wu*.Design, Synthesis, and Bioactivity of Spiro Derivatives Containing a Pyridine Moiety, [J].Journal of Agricultural and Food Chemistry, 2022 ,70 (50) , 15726–15736.

15. Fang-zhouXu, Yan-yan Wang,Sheng-xinGuo, A-liDai, Jian Wu*. Diamide derivatives containing a trifluoromethylpyridine skeleton: Design, synthesis, and insecticidal activity[J]. Journal of Integrative Agriculture, 2022, 21(10), 2995-3003.

16. Zhiguo Zheng, Ali Dai, Zhichao Jin, Yonggui Robin Chi*,Jian Wu*. Trifluoromethylpyridine: An Important Active Fragment for the Discovery of New Pesticides[J]. Journal of Agricultural and Food Chemistry, 2022, 70(36), 11019-11030

17. Renfeng Zhang, Shengxin Guo, Peng Deng, Ya Wang, Ali Dai, Jian Wu* Novel Ferulic Amide Ac6c Derivatives: Design, Synthesis, and Their Antipest Activity[J]. Journal of Agricultural and Food Chemistry,2021, 69(35):10082-10092

18. Wei Zhang, Shengxin. Guo, Ya. Wang, Hong Tu, Lijiao Yu, Zhichao Zhao, Zhenchao Wang, Jian Wu*. Novel trifluoromethylpyridine piperazine derivatives as potential plant activators[J]. Frontiers in Plant Science, 2022, 28, 13:1086057

19. Dexia Luo, Shengxin Guo, Feng He, Shunhong Chen, Ali Dai, Renfeng Zhang, Wu Jian*. Design, Synthesis, and Bioactivity of alpha-Ketoamide Derivatives Bearing a Vanillin Skeleton for Crop Diseases[J]. Journal of Agricultural and Food Chemistry, 2020, 68(27), ‏7226-7234.

20. ShengxinGuo,WeiZhao,YanyanWang,WeiZhang,ShunhongChen, PanpanWei, Jian Wu*. Design, Synthesis, and Mechanism of Antiviral Acylurea Derivatives Containing a Trifluoromethylpyridine Moiety[J].Journal of Agricultural and Food Chemistry, 2021, 69 (43) , 12891-12899

21. Yanyan Wang, Fangzhou Xu, Dexia Luo, Shengxin Guo, Feng He, Ali Dai, Baoan Song, Jian Wu*. Synthesis of Anthranilic Diamide Derivatives Containing Moieties of Trifluoromethylpyridine and Hydrazone as Potential Anti-Viral Agents for Plants[J]. Journal of Agricultural and Food Chemistry, 2019, 67(48), 13344–13352.

22. Shengxin Guo, Feng He, Baoan, Song * Jian Wu.* Future direction of agrochemical development for plant disease in China [J]. Food and Energy Security, 2021, DOI: 10.1002/fes3.293.

23. Zi-Chang Jia, Xue Yang, Xuan-Xuan Hou, Yong-Xin Nie, Jian Wu*The Importance of a Genome-Wide Association Analysis in the Study of Alternative Splicing Mutations in Plants with a Special Focus on Maize[J].International Journal of Molecular Sciences, 2022, 23(8), 4201.

24. Ali Dai, Yuanqin Huang, Lijiao Yu, Zhiguo Zheng, Jian Wu* Design, synthesis, and bioactivity of ferulic acid derivatives containing an beta-amino alcohol[J].BMC Chemistry, 2022, 16(1): 34.

25. Dexia Luo, Shengxin Guo, Feng He, Heying Wang, Fangzhou Xu, Ali Dai, Renfeng Zhang, Jian Wu *. Novel anthranilic amide derivatives bearing the chiral thioether and trifluoromethylpyridine: Synthesis and bioactivity[J]. Bioorganic & Medicinal Chemistry Letters, 2019,30(3),126902.

26. Fangzhou Xu, Shengxin Guo, Wei Zhang, Yanyan Wang, Panpan Wei, Shunhong Chen, Jian Wu*. Trifluoromethylpyridine thiourea derivatives: design, synthesis and inhibition of the self-assembly of tobacco mosaic virus particles[J]. Pest Management Science,2022, 78(4):1417-1427

27. Ali Dai,YuanqinHuang, LijiaoYu,ZhiguoZheng,Jian Wu.* Design, synthesis, and bioactivity of ferulic acid derivatives containing an beta-amino alcohol[J]. BMC Chemistry, 2022, 16(1),34

28. Yaming Liu, Shunhong Chen, Panpan Wei, Shengxin Guo, Jian Wu.*A briefly overview of the research progress for the abscisic acid analogues[J] Frontier in Chemistry, 2022, 10: 967404.

29. Fangzhou Xu, Yanyan Wang, Feng He, Zelian Li, Shengxin Guo, Yun Xie, Dexia Luo, Jian Wu*. Facile construction of spiroindoline derivatives as potential anti-viral agent via three-component reaction in aqueous with beta-cyclodextrin-SO₃H as an efficient catalyst[J]. Green Chemistry Letters and Reviews, 2022,15, 137-150.

30. Ali Dai, Zhiguo Zheng, Lijiao Yu, Yuanqin Huang, Jian Wu*. 1,3,4-Oxadiazole Contained Sesquiterpene Derivatives: Synthesis and Microbiocidal Activity for Plant Disease[J] Frontier in Chemistry, 2022, 10: 854274.

31. Jian Wu, Baoan Song,∗ Deyu Hu, Min Yue, Song Yang.∗ Design, synthesis and insecticidal activities of novel pyrazole amides containing hydrazone substructures[J].Pest Management Science, 2012, 68, 801–810.

32. Feng He, Panpan Wei, Gang Yu, Shengxin Guo, Zhiguo Zheng, Shunhong Chen, Ali Dai, Renfeng Zhang, Zengxue Wu, Jian Wu*. Synthesis of trans- methyl ferulate bearing an oxadiazole ether as potential activators for controlling plant virus. Bioorganic Chemistry,2021, 115:105248.

33. Shunhong Chen, Shengxin Guo, Feng He, Yingxia Zhang, Zengxue Wu, Jian Wu*. DBU Catalyzed Phospho-Aldol-Brook Rearrangement for Rapid Preparation of alpha-Phosphates Amide in Solvent-Free Conditions[J]. Catalysts, 2020, 10(12), 1445.

34. Gang Yu, Shunhong Chen, Shengxin Guo, Bixue Xu, and Jian Wu*, Trifluoromethylpyridine 1,3,4-Oxadiazole Derivatives: Emerging Scaffolds as Bacterial Agents[J]. ACS Omega  2021, 6, 46, 31093-31098

35. Guo Shengxin, He Feng, Dai Ali, Zhang Renfeng, Chen Sshunhong, Wu Jian*. Synthesis and biological activities of novel trifluoromethylpyridine amide derivatives containing sulfur moieties[J]. RSC Advances, 2020, 10(59), 35658-35670.

36. Renfeng Zhang, Peng Deng, Ali Dai, Shengxin Guo, Ya Wang, Panpan Wei, Jian Wu*. Design, Synthesis, and Biological Activity of Novel Ferulic Amide Ac5c Derivatives. ACS Omega, 2021, 6(41), 27561-27567  

37. Feng He, Sheng-Xin Guo, A-Li Dai, Ren-Feng Zhang, Jian Wu * Synthesis, characterization, and biological activity of novel trifluoromethylpyridine amide derivatives[J]. Chinese Journal of Organic Chemistry,2021, doi: 10.6023/cjoc202101045.

38. A-LiDai, Ren-Feng Zhang, Chuan-Hui Li, Li-Jiao Yu, Ya Wang, Jian Wu * Synthesis and Biological Activity of N-Cyano Sulfonimide Derivatives bearing a Trifluoromethyl Pyridinamide[J]. Chinese Journal of Organic Chemistry, 2021, 10.6023/cjoc202102017.

39. Jian Wu, Chaoqun Huang, Jian Wang, Deyu Hu, Linhong Jin, Song Yang, Baoan Song *. Separation, interconversion, and insecticidal activity of the cis- and trans-isomers of novel hydrazone derivatives[J].Journal of Separation Science, 2013, 36(3): 602–608

40. Fangzhou Xu, Yanyan Wang,† Dexia Luo, Gang Yu, Shenxing Guo, Huan Fu, Yonghui Zhao, Jian Wu*, Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety[J].RSC Advances, 2018, 8, 6306–6314.

41. Yanyan Wang, Fangzhou Xu, Yunying Zhu, Wei Xue, Baoan Song, Jian Wu.* Synthesis, anti-viral activities and molecular docking of pyrazolo[3,4-d]pyrimidine derivatives containing Schiff base[J].Bioorganic & Medicinal Chemistry Letters,2018, 28, 2979–2984.

42. Fangzhou Xu, Yanyan Wang, Dexia Luo, Gang Yu, Yikun Wu, Ali Dai, Yonghui Zhao, Jian Wu* Novel trifluoromethyl pyridine derivatives bearing an 1, 3, 4-oxadiazole moiety as potential insecticide[J]. ChemistrySelect, 2018, 3: 2795 – 2799.

43. Gang Yu, Lijun Luo, Shunhong Chen, Feng He, Yun Xie, Dexia Luo, Wei Xue,* Jian Wu.* Synthesis and Insecticidal Activity of Novel Diacylhydrazines Derivatives Containing a N-Pyrazolepyrazole Moiety[J]. ChemistrySelect, 2018, 3, 10991– 10995.

44. Yanyan Wang, Xiumian Lu, Jun Shi, Jiahong Xu, Fenghua Wang, Xiao Yang, Gang Yu, Zhiqian Liu, Chuanhui Li, Ali Dai, Yonghui Zhao, Jian Wu. Synthesis and larvicidal activity of 1,3,4-oxadiazole derivatives containing a 3-chloropyridin-2-yl-1H-pyrazole scaffold[J].Monatshefte für Chemie - Chemical Monthly, 2018, 149: 611–623.

45. Jian Wu,* Fang-Zhou Xu,^# She-Lei Feng, Wei Xue, and Zhen-Zhen Wang, A facile preparation of imidazo[1,2-a]pyridin-3-amine derivatives via a three-component reaction with -cyclodextrin–SO₃H as catalyst[J].Heterocycles, 2016, 92(9), 1629-1642（High light by Synfact）

46. Yanyan Wang , Fanzhou Xu, Gang Yu, Jun Shi, Chuanhui Li, A’li Dai, Zhiqian Liu, Jiahong Xu, Fenghua Wang, Jian Wu*, Synthesis and insecticidal activity of diacylhydrazine derivatives containing a 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole scaffold. Chemistry Central Journal, 2017, 11 (1) :50

47. Jian Wu*, Yun-Ying Zhu, Yong-Hui Zhao, Wei-Li Shan, De-Yu Hu, Ji-Xiang Chen, Xiang-Yang Li, Song Yang. Synthesis and antiviral activities of novel 1,4-pentadien-3-one derivatives bearing an emodin moiety[J]. Chinese Chemical Letters, 2016, 27, 948–952.

48. Fang-Zhou Xu, Jia-Hui Shao, Yun-Ying Zhu, Li-Wei Liu, Yong-Hui Zhao, Wei-Li Shan, Yan-Yan Wang, Jian Wu*, Song Yang, Wei Xue. Synthesis, antifungal and insecticidal activity of novel [1,2,4]triazolo[4,3-a]pyridine derivatives containing a sulfide substructure[J]. Chemical Papers, 2017, 71(4), 729–739.

49. Jian Wu*, Dan-Dan Xie, Wei-Li Shan, Yong-Hui Zhao, Wei Zhang,Baoan Song, Song Yang, Juan Ma. Synthesis and insecticidal activity of anthranilic diamides with hydrazine substructure[J]. Chemical Papers, 2015, 6 9(7) , 993-1003.

50. Jian Wu*, Song Bai, Min Yue, Li-Jun Luo, Qin-Cai Shi, Juan Ma, Xian-Li Du, Sheng-Hong Kang, Deyu Hu, Song Yang. Synthesis and insecticidal activity of 6,8-dichloro-quinazoline derivatives containing a sulfide substructure[J].Chemical Papers, 2014, 68(7), 969–975.

51. Jian Wu, Sheng-hong Kang, Li-jun Luo, Qing-cai Shi, Juan Ma, Juan Yin, Bao-an Song, De-yu Hu, Song Yang. Synthesis and Antifungal Activities of novel Nicotinamide Derivatives containing 1,3,4-Oxadiazole[J].Chemistry Central Journal, 2013,7,64.

52. Jian Wu, Qing Shi, Zhuo Chen, Ming He, Linhong Jin, Deyu Hu. Synthesis and Bioactivity of Pyrazole Acyl Thiourea Derivatives[J]. Molecules, 2012, 17(5), 5139-5150.

53. Jian Wu*, Shenghong Kang, Qinkun Yuan, Lijun Luo, Juan Ma, Qingcai Shi and Song Yang. N-Substituted 5-Chloro-6-phenyl pyridazin-3(2H)-ones: Synthesis, Insecticidal Activity Against Plutella xylostella (L.) and SAR Study[J]. Molecules, 2012, 17(8), 9413-9420.

54. Jian Wu, Shenghong Kang, Baoan Song Deyu Hu, Ming He, Linhong Jin, Song Yang Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazine derivatives containing a pyridine moiety [J]. Chemistry Central Journal, 2012, 6, 28.

55. Jian Wu, Jian Wang, Deyu Hu, Ming He, Linhong Jin, Baoan Song. Synthesis and antifungal activity of novel pyrazolecarboxamide derivatives containing a hydrazone moiety [J]. Chemistry Central Journal, 2012, 6, 51 (SCI, IF. 1.312）

56. Jian Wu, Wenshi Yi, Linhong Jin, Deyu Hu, Baoan Song. Antiproliferative and cell apoptosis inducing activities of compounds from Buddleja davidii in Mgc-803 cells [J]. Cell Division, 2012, 7(1), 20.

57. Jian Wu, Baoan Song, Synthesis and Insecticidal Activities of Novel Neonicotinoid Analogues Bearing an Amide Moiety[J].Journal of Heterocyclic Chemistry, 2011, 14 (9): 3676-3687.

58. Sheng-Hong Kang, Bao-an Song, Jian Wu, Min He, De-Yu Hu, Lin-hong Jin, Song Zeng, Wei Xue, Song Yang. Design, synthesis and insecticidal activities of novel acetamido derivatives containing N-pyridylpyrazole carboxamides[J]. European Journal of Medicinal Chemistry, 2013, 67,14-18.

59. Jian Wu, Baoan Song* Research progress of anti-virus agents for plants in China, SCIENTIA SINICA Chimica,2016, 46(11), 1165-1179 (in Chinese).

60. Fang-Zhou Xu, Yan-Yan Wang, Yun-Ying Zhu, Jia-Hui Shao, Gang Yu, Wei Xue, Jian Wu*, Hui-Bing Wu, Jun Shi, Synthesis and biological activity of novel sulfone derivatives containing a [1,2,4]triazolo[4,3-a]pyridine moiety[J]. Phosphorus, Sulfur, and Silicon and the Related Elements, 2017, 192(7), 850-855.

发明专利

1. 吴剑, 罗德霞, 郭声鑫, 代阿丽, 何凤, 陈顺红. 含α-羰基酰胺结构的醚类乙酰胺衍生物及其应用, CN201910809656.0；申请日：2019-08-29；授权公告日：2023-03-21.

2. 吴剑, 王艳艳, 徐方舟, 罗德霞, 郭声鑫, 代阿丽, 何凤, 陈顺红. 一种含三氟甲基吡啶二甲酰胺的席夫碱的衍生物及其应用, 申请(专利)号：CN 201910810123.4；申请日：2019-08-29；授权公告日：2022-09-23

3. 吴剑, 张仁凤, 郭声鑫, 陈顺红, 魏盼盼, 郑志国.一种阿魏酸酰胺衍生物及其合成方法, 申请(专利)号：CN 202110537257.0；申请日：2021-05-18；授权公告日：2022-07-01.

4. 徐方舟, 吴剑, 罗德霞, 郭声鑫, 何凤, 张仁凤, 陈顺红. 一种含三氟甲基吡啶的酰基硫脲或酰基脲类衍生物及其应用，申请(专利)号：CN 201910810477.9；申请日：2019-08-29,  授权公告日：2022-05-03

5. 吴剑, 王艳艳, 徐方舟, 寻曦炜, 黎泽莲, 罗德霞, 陈顺红, 薛伟. 一种N-杂环酰胺衍生物的合成方法. CN 201811093557.9；申请日：2018-09-19；授权公告日：2022-02-18.

6. 吴剑, 徐方舟, 王艳艳, 寻曦炜, 黎泽莲, 罗德霞, 陈顺红, 薛伟. 一种α-羰基酰胺衍生物的制备方法. 申请(专利)号：CN 201811016732.4；申请日：2018-09-03；授权公告日：2021-03-02

7. 吴剑, 徐方舟, 王艳艳, 罗德霞, 薛伟. 一种三氟甲基吡啶联噁二唑(醚)类衍生物及其应用. 申请(专利)号：CN201810060462.0；申请日：2018-01-22；授权公告日：2020-12-18

8. 吴剑, 余刚, 张建, 陈顺红, 何凤, 薛伟. 一种醚类化合物在促进植物生长方面的应用. 申请(专利)号：CN 201811094170.5；申请日：2018-09-19；授权公告日：2020-10-27

9. 吴剑, 徐方舟, 薛伟, 宋宝安, 刘登曰, 陈吉祥, 胡德禹, 杨松. 吡唑[3,4-d]嘧啶酮席夫碱类化合物在制备抗植物病毒剂中的应用. 申请(专利)号：CN 201610490135.X申请日：2016-06-29；授权公告日：2018-11-30.

10. 吴剑, 徐方舟, 薛伟, 刘登曰, 陈吉祥. 5-氨基-1H-吡唑[3,4-d]嘧啶-4(5H)-酮类化合物在制备抗植物病毒剂中的应用. 申请(专利)号：CN 201610463022.0；申请日：2016-06-23；授权公告日：2018-10-23.

11. 吴剑, 宋宝安, 薛伟, 胡德禹, 杨松, 杜显丽, 骆礼军, 马娟, 史庆才. 一种制备2,3-二氢喹唑啉-4(3H)-酮类衍生物的方法. 申请(专利)号：CN 201310501589.9；申请日：2013-10-23；授权公告日：2016-06-08

12. 宋宝安, 吴剑, 杨松, 金林红, 岳敏, 杰杰乌, 王贞超, 胡德禹. 含杂环酰胺结构的酰腙及肟酯类化合物及其应用. 申请(专利)号：CN 201010560706.5；申请日：2010-11-26；授权公告日：2014-04-02

13. 宋宝安, 吴剑, 杨松, 金林红, 岳敏, 杰杰乌, 王贞超, 胡德禹. 一类酰腙和酰肼衍生物及其应用. 申请(专利)号：CN 201010560727.7；申请日：2010-11-26；授权公告日：2013-04-17.

14. 宋宝安, 吴剑, 薛伟, 陈鹏丽, 杨松, 曾松, 胡德禹, 王贞超, 徐维明. 1,5-二取代芳基-1,4-戊二烯-3-酮肟醚类化合物及其制备方法和杀虫活性应用.申请(专利)号：CN 201010272708.4；申请日：2010-09-06；授权公告日：2012-06-27.

代表性国际会议报告

1. Xu Fangzhou, Wang Yanyan, Yu Gang, Wang Fenghua, Wu Jian *. A Facile Selective Synthesis of Spiro[indoline-3,9'-xanthene] Derivatives Based on Acidic/Basic Condition in Water, International Conference on New Challenges in Organic Synthesis, International Conference on Organic Chemistry, Guangzhou, China, 2016.11.26-2016.11.29.

2. Wu Jian*. Synthesis and Insecticidal Activities of novel Ppyrazole Amides containing Hydrazone Substructures., 4th International Symposium on Pesticide and Environmental Safety; 5th Pan Pacific Conference on Pesticide Science; 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization., Beijing, 2012.9.17-2012.9.20.

3. Wu Jian*, Song Baoan. Current Situation and Prospect of Green Development for Pesticide in China. The 2nd International Conference on Insect Pest Management. Guiyang, China. 2019.07.28-2019.07.31.

4. Wu Jian*, Song Baoan. Current Situation and Prospect of Green Development for Pesticide in China. The China ASEAN Advanced Forum on Agrochemicals. Nanning, China. 2019.09.25-2019.09.26.

5. Wu Jian*, Current Situation and Prospect of Green Development for Pesticide in China, The Second International Conference On Green Protection Innovation. Guiyang, China. 2019.10.20-2019.10.23.

6. Wu Jian*, Song Baoan. Innovation of agrichemicals for plant disease: The current situation and future. ACS Fall 2020 Virtual Meeting & Expo, Los Angeles USA (Online), 2020.8.16-2020.8.20.

7. Wu Jian*. The Current Situation and Prospect of Agrochemical Innovatin for Plant Diseases. Sino-European Plant Protection Young Scientists Forum – Utilization and Protection of Agricultural Crops in the Post-Covid-19 Era, Guiyang, China (Online), 2020.12.09-2020.12.12.

奖励/荣誉情况

1. 2023年，国家教学成果二等奖，植物保护专业“农生化交叉、产教研融合”人才培养模式的构建与实践，4/13；

2. 2020年，中国石油与化学工业联合会优秀出版物奖-图书奖一等奖，农药产业，1/5；

3. 2021年，第四届贵州省研究生教育成果特等奖，新时代农药学科创新型人才培养体系的构建与实践，3/7；

4. 2021年，贵州省科技进步一等奖，茶园主要病虫草害绿色高效防控技术体系创建与应用，7/9；

5. 2022年，大北农科技奖一等奖，茶园病虫草害绿色防控关键技术研究，5/10；

6. 2021年，贵州省“最美科技工作者”，1/1；

7. 2022年，第十届贵州省高等教育教学成果特等奖，植物保护专业人才培养模式的改革与实践，3/8；

8. 2023年，贵州大学2022年度“大北农奖”——优秀教师奖；

9. 2020年，贵州大学“书记校长特别嘉奖”；

10. 2020年，贵州大学“清原绿色农药奖”；

11. 2023年，贵州大学2022年度“书记校长特别嘉奖”。