吴剑教授简历

个人简介

吴剑，博士，1981年12月生，教授，博士生导师，入选国家级高层次人才、省部级青年人才、贵州省“重点联系省管专家”等。2010年12月在贵州大学获得农药学博士学位，随后留校从事教学科研工作。兼任中国化工学会第41届理事、中国化工学会第九届农药专委会委员、中国生物工程学会生物农业分会委员、《现代农药》副主编、《农药学学报》青年编委、国际期刊BMC Chemistry 编委。在国内外主要学术会议上作邀请报告20余次。参与出版专著及教材6部。

聚焦我国绿色农药缺乏原创性分子结构、清洁化生产技术短缺等科学问题和技术需求。开展基于天然产物、含氟杂环为主导的绿色农药的创制研究工作，发现10余个高活性先导及1个候选农药，申请国家发明专利20余项（获14项授权），其中“一种醚类化合物在促进植物生长方面的应用（ZL 2018110941705）”的专利以1000万元转让给鹤壁全丰生物科技有限公司进行产业化开发。迄今为止，作为第一/通讯作者在Angew. Chem. Int. Ed，Green Chemistry，Journal of Agricultural.and food Chemistry, Food and Energy Security等发表SCI论文60余篇。获中国石油和化学工业联合会优秀出版物一等奖、国家教育教学成果二等奖、贵州省教育教学成果特等奖、贵州省“最美科技工作者”等荣誉称号。

工作经历

教育经历

学术兼职

教学工作

本科生课程：

1. 农药化学（参讲）

2. 有机化学1-1（主讲）

3. 科研素质创新能力培养1（主讲）

4. 新农药发现前沿讲座（主讲）

5. 有机化学强基课程（参讲）

6. 科技论文检索与写作（主讲）

研究生课程：

1. 农药学（主讲）

2. 科技文献检索与论文写作（主讲）

  研究方向

1. 绿色农药的设计、合成及构效关系研究；

2. 有机合成；

3. 有机功能分子的合成研究；

4. 活性分子的作用机制。

代表性科研项目

1. 国家级领军人才项目，2022-01-01 ~ 2024-01-01

2. 国家自然科学基金委，新型酰腙类抗植物病毒衍生物的设计、合成及作用机制研究（32072445），2021-01-01 ~ 2024-12-31

3. 国家自然科学基金委，含三氟甲基吡啶杀虫化合物的结构多样性衍生与作用机制初探（21762012），2018-01-01 ~ 2021-12-01

4. 国家自然科学基金委，含氟取代(亚)磺酰基杂环衍生物的设计合成与生物活性研究(21562012),2016-01-01 ~ 2019-12-01

5. 国家自然科学基金委，新型含喹唑啉结构的吡唑酰胺衍生物的设计、合成及生物活性研究(21302025)2014-01-01 ~ 2016-12-01

6. 国家自然科学基金委，新型含酰腙结构吡唑酰胺衍生物的设计合成及杀虫活性研究(21162004)2012-01-01 ~ 2015-12-01

7. 国家科技部，高效低风险农药学科创新引智基地（111引智基地）, 2020-01-01 ~ 2025-12-31

8. 贵州省科技厅，新型杂环衍生物的设计合成及生物活性研究(黔科合人字（2015）15号，贵州省优秀青年科技人才项目),2015-09-22 ~ 2018-08-01

9. 贵州省科技厅，以天然产物阿魏酸为导向的新型抗植物病毒剂的创制研究(黔科合基础[2017]1402，重点项目)，2017-10-01 ~ 2021-10-01

10. 贵州省科技厅，新型吡唑酰胺类衍生物的合成及生物活性研究（黔科合J字[2014]2056号），2014-08-01~ 2017-08-01

11. 贵州省教育厅，新型含腙类结构的邻苯二甲酰胺衍生物的设计合成及杀虫活性研究（黔省专合字（2011）38号），2011-09-20 ~ 2014-09-20

12. 农业农村部种植业管理司，农药行业管理支撑服务--农药按毒性分类登记资料要求调研, 2022-05-18~2022-11-30

13. 农业农村部人才培养计划项目，2021-09-30 ~ 2022-04-30

14. 山东润丰，氯虫苯甲酰胺路线开发，2021-07-30~ 2021-08-31

15. 农业农村部种植业管理司，农业投入品综合管理服务, 2021-04-02 ~ 2021-11-30

16. 农业农村部种植业管理司，农药产业科技创新支撑服务, 2020-06-10 ~ 2020-09-3

17. 农业农村部种植业管理司，农药产品中有效成分测定通用分析方法—液相色谱法》体系建设：氨磺乐灵等8个农药品种液相色谱分析方法建立, 2019-11-15~ 2021-03-31

18. 农业农村部农药检定所，我国主要农药品种特性、理化等相关数据采集和分析，2018-08-01 ~2018-12-01

19. 农业农村部农药检定所，我国新农药创制研究及应用现状调研, 2015-02-01~ 2015-06-01中国农业出版社，中国农业百科文字资源委托建设, 2018-06-13 ~2019-06-01

20. 贵州大学，含杂环新型邻苯二甲酰胺类衍生物的设计合成及生物活性研究(贵大人基合字（2011）24号), 2012-01-01 ~ 2013-12-01

21. 贵州大学，ABA功能类似物合成及作用机制, 2020-11-01 ~ 2023-11-30.

代表性专著及论文

专著：

1. 吴  剑，李钟华. 《农药产业》，2019年，化学工业出版社；

2. 宋宝安，吴  剑. 《农药合成》，2017年，中国农业出版社；

3. 宋宝安，吴  剑. 《新杂环农药——除草剂》，2011年，化学工业出版社；

4. 王鸣华，宋宝安，吴  剑，等. 《农药立体化学》，2016年，化学工业出版社；

5. 宋宝安，金林红，等. 《新杂环农药——杀虫剂》，2010年，化学工业出版社（副主编）；

6. 宋宝安. 《新杂环农药——杀菌剂》，2009年，化学工业出版社（参编）；

论文：

1. Guoyong Luo, Zhijian Huang, Shitian Zhuo, Chengli Mou, Jian Wu *, Zhichao Jin, Yonggui Robin Chi*. Access to Cyclic beta-Amino Acids by Amine-Catalyzed Enantioselective Addition of the gamma-Carbon Atoms of alpha,beta-Unsaturated Imines to Enals[J].Angewandte Chemie-International Edition,2019, 58(48), 17189-17193.

2. Jian Wu,* Xianli Du, Juan Ma, Yuping Zhang, Qingcai Shi, Lijun Luo, Baoan Song,* Song Yang, Deyu Hu. Preparation of 2,3-dihydroquinazolin-4(1H)-one derivatives in aqueous media with α-cyclodextrin-SO₃H as a recyclable catalyst[J]. Green Chemistry, 2014, 16, 3210–3217.

3. Jiamiao Jin, Tingwei Shen, Liangzhen Shu, Yixian Huang, Youlin Deng, Benpeng Li, Zhichao Jin*, Xiangyang Li*, and Jian Wu*. Recent Achievements in Antiviral Agent Development for Plant Protection[J] Journal of Agricultural and Food Chemistry,2023, 71(3): 1291-1309.  

4. Dongyu Chen; Hui Huang; Yuanqin Huang; Weicheng Yang; Weili Shan; Gefei Hao*; Jian Wu*; Baoan Song. Toxicity Tests for Chemical Pesticide Registration: Requirement Differences among the United States, the European Union, Japan, and China?[J] Journal of Agricultural and Food Chemistry,2023, https://doi.org/10.1021/acs.jafc.3c00410 .  

5. Wei Zhang, Shengxin Guo , Lijiao Yu, Ya Wang, Yonggui Robin Chi,*Jian Wu*. Piperazine: Its role in the discovery of pesticides[J].Chinese Chemical Letters, 2023, doi:https://doi.org/10.1016/j.cclet.2022.108123.

6. Shengxin Guo; Feng He; Wei Zhang; Ya Wang; Lijiao Yu; Jian Wu*. Fluorinated or brominated meta‐diamides as the new scaffolds for the treatment of rice bacterial leaf blight[J]. Food and Energy Security, 2023, doi:https://doi.org/10.1002/fes3.449.

7. Ya Wang, Shengxin Guo, Lijiao Yu, Wei Zhang, Zhenchao Wang,* Yonggui Robin Chi*, Jian Wu*. Hydrazone derivatives in agrochemical discovery and development [J]. Chinese Chemical Letters, 2023,doi:https://doi.org/10.1016/j.cclet.2023.108207

8. Wei Zhang, Shengxin Guo, Ya Wang, Yikun Wu, Lijiao Yu, Jian Wu*. Trifluoromethylpyridine piperazine derivatives: synthesis and anti-plant virus activity[J].Pest Management Science, 2023,doi:https://doi.org/10.1002/ps.7429

9. Zhiguo Zheng; Shunhong Chen; Panpan Wei; Shengxin Guo; Gang Yu; Jian Wu*. The proteomics and metabolomics studies of GZU001 on promoting the Merisis of maize (Zea mays L.) roots [J]. BMC Plant Biology, 2023, 23, 103.

10. Ping Sun, Yuanqin Huang, Xiaoyan Yang, Anjing Liao, Jian Wu*. The role of indole derivative in the growth of plants: A review[J]. Frontiers in Plant Science, 2023, 13: 1120613.  

11. Ali Dai, Zhiguo Zheng, Yuanqin Huang, Lijiao Yu, Zhenchao Wang *, Jian Wu*. Hydrazone modification of non-food natural product sclareolide as potentialagents for plant disease[J]. Heliyon, 2023, 8, e12391.

12. XinyuZhang, JinliZhang,JieChen,Banghua Zhou,JianZhang,Shunhong Chen,Jian Wu*,YaojiaJiang*. Modular synthesis of fluorinated 2H-thiophenes via [4 + 1] cyclization of enaminothiones[J]. Organic & Biomolecular Chemistry, 2023, 2023,21, 3345-3349

13. LijiaoYu,AliDai,WeiZhang,AnjingLiao,ShengxinGuo, Jian Wu* Spiro Derivatives in the Discovery of New Pesticides: A Research Review[J].Journal of Agricultural and Food Chemistry, 2022,70(35) , 10693-10707.

14. Lijiao Yu, Shengxin Guo, Ya Wang, Anjing Liao, Wei Zhang, Ping Sun, and Jian Wu*.Design, Synthesis, and Bioactivity of Spiro Derivatives Containing a Pyridine Moiety, [J].Journal of Agricultural and Food Chemistry, 2022 ,70 (50) , 15726–15736.

15. Fang-zhouXu, Yan-yan Wang,Sheng-xinGuo, A-liDai, Jian Wu*. Diamide derivatives containing a trifluoromethylpyridine skeleton: Design, synthesis, and insecticidal activity[J]. Journal of Integrative Agriculture, 2022, 21(10), 2995-3003.

16. Zhiguo Zheng, Ali Dai, Zhichao Jin, Yonggui Robin Chi*,Jian Wu*. Trifluoromethylpyridine: An Important Active Fragment for the Discovery of New Pesticides[J]. Journal of Agricultural and Food Chemistry, 2022, 70(36), 11019-11030

17. Renfeng Zhang, Shengxin Guo, Peng Deng, Ya Wang, Ali Dai, Jian Wu* Novel Ferulic Amide Ac6c Derivatives: Design, Synthesis, and Their Antipest Activity[J]. Journal of Agricultural and Food Chemistry,2021, 69(35):10082-10092

18. Wei Zhang, Shengxin. Guo, Ya. Wang, Hong Tu, Lijiao Yu, Zhichao Zhao, Zhenchao Wang, Jian Wu*. Novel trifluoromethylpyridine piperazine derivatives as potential plant activators[J]. Frontiers in Plant Science, 2022, 28, 13:1086057

19. Dexia Luo, Shengxin Guo, Feng He, Shunhong Chen, Ali Dai, Renfeng Zhang, Wu Jian*. Design, Synthesis, and Bioactivity of alpha-Ketoamide Derivatives Bearing a Vanillin Skeleton for Crop Diseases[J]. Journal of Agricultural and Food Chemistry, 2020, 68(27), ‏7226-7234.

20. ShengxinGuo,WeiZhao,YanyanWang,WeiZhang,ShunhongChen, PanpanWei, Jian Wu*. Design, Synthesis, and Mechanism of Antiviral Acylurea Derivatives Containing a Trifluoromethylpyridine Moiety[J].Journal of Agricultural and Food Chemistry, 2021, 69 (43) , 12891-12899

21. Yanyan Wang, Fangzhou Xu, Dexia Luo, Shengxin Guo, Feng He, Ali Dai, Baoan Song, Jian Wu*. Synthesis of Anthranilic Diamide Derivatives Containing Moieties of Trifluoromethylpyridine and Hydrazone as Potential Anti-Viral Agents for Plants[J]. Journal of Agricultural and Food Chemistry, 2019, 67(48), 13344–13352.

22. Shengxin Guo, Feng He, Baoan, Song * Jian Wu.* Future direction of agrochemical development for plant disease in China [J]. Food and Energy Security, 2021, DOI: 10.1002/fes3.293.

23. Zi-Chang Jia, Xue Yang, Xuan-Xuan Hou, Yong-Xin Nie, Jian Wu*The Importance of a Genome-Wide Association Analysis in the Study of Alternative Splicing Mutations in Plants with a Special Focus on Maize[J].International Journal of Molecular Sciences, 2022, 23(8), 4201.

24. Ali Dai, Yuanqin Huang, Lijiao Yu, Zhiguo Zheng, Jian Wu* Design, synthesis, and bioactivity of ferulic acid derivatives containing an beta-amino alcohol[J].BMC Chemistry, 2022, 16(1): 34.

25. Dexia Luo, Shengxin Guo, Feng He, Heying Wang, Fangzhou Xu, Ali Dai, Renfeng Zhang, Jian Wu *. Novel anthranilic amide derivatives bearing the chiral thioether and trifluoromethylpyridine: Synthesis and bioactivity[J]. Bioorganic & Medicinal Chemistry Letters, 2019,30(3),126902.

26. Fangzhou Xu, Shengxin Guo, Wei Zhang, Yanyan Wang, Panpan Wei, Shunhong Chen, Jian Wu*. Trifluoromethylpyridine thiourea derivatives: design, synthesis and inhibition of the self-assembly of tobacco mosaic virus particles[J]. Pest Management Science,2022, 78(4):1417-1427

27. Ali Dai,YuanqinHuang, LijiaoYu,ZhiguoZheng,Jian Wu.* Design, synthesis, and bioactivity of ferulic acid derivatives containing an beta-amino alcohol[J]. BMC Chemistry, 2022, 16(1),34

28. Yaming Liu, Shunhong Chen, Panpan Wei, Shengxin Guo, Jian Wu.*A briefly overview of the research progress for the abscisic acid analogues[J] Frontier in Chemistry, 2022, 10: 967404.

29. Fangzhou Xu, Yanyan Wang, Feng He, Zelian Li, Shengxin Guo, Yun Xie, Dexia Luo, Jian Wu*. Facile construction of spiroindoline derivatives as potential anti-viral agent via three-component reaction in aqueous with beta-cyclodextrin-SO₃H as an efficient catalyst[J]. Green Chemistry Letters and Reviews, 2022,15, 137-150.

30. Ali Dai, Zhiguo Zheng, Lijiao Yu, Yuanqin Huang, Jian Wu*. 1,3,4-Oxadiazole Contained Sesquiterpene Derivatives: Synthesis and Microbiocidal Activity for Plant Disease[J] Frontier in Chemistry, 2022, 10: 854274.

31. Jian Wu, Baoan Song,∗ Deyu Hu, Min Yue, Song Yang.∗ Design, synthesis and insecticidal activities of novel pyrazole amides containing hydrazone substructures[J].Pest Management Science, 2012, 68, 801–810.

32. Feng He, Panpan Wei, Gang Yu, Shengxin Guo, Zhiguo Zheng, Shunhong Chen, Ali Dai, Renfeng Zhang, Zengxue Wu, Jian Wu*. Synthesis of trans- methyl ferulate bearing an oxadiazole ether as potential activators for controlling plant virus. Bioorganic Chemistry,2021, 115:105248.

33. Shunhong Chen, Shengxin Guo, Feng He, Yingxia Zhang, Zengxue Wu, Jian Wu*. DBU Catalyzed Phospho-Aldol-Brook Rearrangement for Rapid Preparation of alpha-Phosphates Amide in Solvent-Free Conditions[J]. Catalysts, 2020, 10(12), 1445.

34. Gang Yu, Shunhong Chen, Shengxin Guo, Bixue Xu, and Jian Wu*, Trifluoromethylpyridine 1,3,4-Oxadiazole Derivatives: Emerging Scaffolds as Bacterial Agents[J]. ACS Omega  2021, 6, 46, 31093-31098

35. Guo Shengxin, He Feng, Dai Ali, Zhang Renfeng, Chen Sshunhong, Wu Jian*. Synthesis and biological activities of novel trifluoromethylpyridine amide derivatives containing sulfur moieties[J]. RSC Advances, 2020, 10(59), 35658-35670.

36. Renfeng Zhang, Peng Deng, Ali Dai, Shengxin Guo, Ya Wang, Panpan Wei, Jian Wu*. Design, Synthesis, and Biological Activity of Novel Ferulic Amide Ac5c Derivatives. ACS Omega, 2021, 6(41), 27561-27567  

37. Feng He, Sheng-Xin Guo, A-Li Dai, Ren-Feng Zhang, Jian Wu * Synthesis, characterization, and biological activity of novel trifluoromethylpyridine amide derivatives[J]. Chinese Journal of Organic Chemistry,2021, doi: 10.6023/cjoc202101045.

38. A-LiDai, Ren-Feng Zhang, Chuan-Hui Li, Li-Jiao Yu, Ya Wang, Jian Wu * Synthesis and Biological Activity of N-Cyano Sulfonimide Derivatives bearing a Trifluoromethyl Pyridinamide[J]. Chinese Journal of Organic Chemistry, 2021, 10.6023/cjoc202102017.

39. Jian Wu, Chaoqun Huang, Jian Wang, Deyu Hu, Linhong Jin, Song Yang, Baoan Song *. Separation, interconversion, and insecticidal activity of the cis- and trans-isomers of novel hydrazone derivatives[J].Journal of Separation Science, 2013, 36(3): 602–608

40. Fangzhou Xu, Yanyan Wang,† Dexia Luo, Gang Yu, Shenxing Guo, Huan Fu, Yonghui Zhao, Jian Wu*, Design, synthesis, insecticidal activity and 3D-QSR study for novel trifluoromethyl pyridine derivatives containing an 1,3,4-oxadiazole moiety[J].RSC Advances, 2018, 8, 6306–6314.

41. Yanyan Wang, Fangzhou Xu, Yunying Zhu, Wei Xue, Baoan Song, Jian Wu.* Synthesis, anti-viral activities and molecular docking of pyrazolo[3,4-d]pyrimidine derivatives containing Schiff base[J].Bioorganic & Medicinal Chemistry Letters,2018, 28, 2979–2984.

42. Fangzhou Xu, Yanyan Wang, Dexia Luo, Gang Yu, Yikun Wu, Ali Dai, Yonghui Zhao, Jian Wu* Novel trifluoromethyl pyridine derivatives bearing an 1, 3, 4-oxadiazole moiety as potential insecticide[J]. ChemistrySelect, 2018, 3: 2795 – 2799.

43. Gang Yu, Lijun Luo, Shunhong Chen, Feng He, Yun Xie, Dexia Luo, Wei Xue,* Jian Wu.* Synthesis and Insecticidal Activity of Novel Diacylhydrazines Derivatives Containing a N-Pyrazolepyrazole Moiety[J]. ChemistrySelect, 2018, 3, 10991– 10995.

44. Yanyan Wang, Xiumian Lu, Jun Shi, Jiahong Xu, Fenghua Wang, Xiao Yang, Gang Yu, Zhiqian Liu, Chuanhui Li, Ali Dai, Yonghui Zhao, Jian Wu. Synthesis and larvicidal activity of 1,3,4-oxadiazole derivatives containing a 3-chloropyridin-2-yl-1H-pyrazole scaffold[J].Monatshefte für Chemie - Chemical Monthly, 2018, 149: 611–623.

45. Jian Wu,* Fang-Zhou Xu,^# She-Lei Feng, Wei Xue, and Zhen-Zhen Wang, A facile preparation of imidazo[1,2-a]pyridin-3-amine derivatives via a three-component reaction with -cyclodextrin–SO₃H as catalyst[J].Heterocycles, 2016, 92(9), 1629-1642（High light by Synfact）

46. Yanyan Wang , Fanzhou Xu, Gang Yu, Jun Shi, Chuanhui Li, A’li Dai, Zhiqian Liu, Jiahong Xu, Fenghua Wang, Jian Wu*, Synthesis and insecticidal activity of diacylhydrazine derivatives containing a 3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole scaffold. Chemistry Central Journal, 2017, 11 (1) :50

47. Jian Wu*, Yun-Ying Zhu, Yong-Hui Zhao, Wei-Li Shan, De-Yu Hu, Ji-Xiang Chen, Xiang-Yang Li, Song Yang. Synthesis and antiviral activities of novel 1,4-pentadien-3-one derivatives bearing an emodin moiety[J]. Chinese Chemical Letters, 2016, 27, 948–952.

48. Fang-Zhou Xu, Jia-Hui Shao, Yun-Ying Zhu, Li-Wei Liu, Yong-Hui Zhao, Wei-Li Shan, Yan-Yan Wang, Jian Wu*, Song Yang, Wei Xue. Synthesis, antifungal and insecticidal activity of novel [1,2,4]triazolo[4,3-a]pyridine derivatives containing a sulfide substructure[J]. Chemical Papers, 2017, 71(4), 729–739.

49. Jian Wu*, Dan-Dan Xie, Wei-Li Shan, Yong-Hui Zhao, Wei Zhang,Baoan Song, Song Yang, Juan Ma. Synthesis and insecticidal activity of anthranilic diamides with hydrazine substructure[J]. Chemical Papers, 2015, 6 9(7) , 993-1003.

50. Jian Wu*, Song Bai, Min Yue, Li-Jun Luo, Qin-Cai Shi, Juan Ma, Xian-Li Du, Sheng-Hong Kang, Deyu Hu, Song Yang. Synthesis and insecticidal activity of 6,8-dichloro-quinazoline derivatives containing a sulfide substructure[J].Chemical Papers, 2014, 68(7), 969–975.

51. Jian Wu, Sheng-hong Kang, Li-jun Luo, Qing-cai Shi, Juan Ma, Juan Yin, Bao-an Song, De-yu Hu, Song Yang. Synthesis and Antifungal Activities of novel Nicotinamide Derivatives containing 1,3,4-Oxadiazole[J].Chemistry Central Journal, 2013,7,64.

52. Jian Wu, Qing Shi, Zhuo Chen, Ming He, Linhong Jin, Deyu Hu. Synthesis and Bioactivity of Pyrazole Acyl Thiourea Derivatives[J]. Molecules, 2012, 17(5), 5139-5150.

53. Jian Wu*, Shenghong Kang, Qinkun Yuan, Lijun Luo, Juan Ma, Qingcai Shi and Song Yang. N-Substituted 5-Chloro-6-phenyl pyridazin-3(2H)-ones: Synthesis, Insecticidal Activity Against Plutella xylostella (L.) and SAR Study[J]. Molecules, 2012, 17(8), 9413-9420.

54. Jian Wu, Shenghong Kang, Baoan Song Deyu Hu, Ming He, Linhong Jin, Song Yang Synthesis and antibacterial activity against ralstonia solanacearum for novel hydrazine derivatives containing a pyridine moiety [J]. Chemistry Central Journal, 2012, 6, 28.

55. Jian Wu, Jian Wang, Deyu Hu, Ming He, Linhong Jin, Baoan Song. Synthesis and antifungal activity of novel pyrazolecarboxamide derivatives containing a hydrazone moiety [J]. Chemistry Central Journal, 2012, 6, 51 

56. Jian Wu, Wenshi Yi, Linhong Jin, Deyu Hu, Baoan Song. Antiproliferative and cell apoptosis inducing activities of compounds from Buddleja davidii in Mgc-803 cells [J]. Cell Division, 2012, 7(1), 20.

57. Jian Wu, Baoan Song, Synthesis and Insecticidal Activities of Novel Neonicotinoid Analogues Bearing an Amide Moiety[J].Journal of Heterocyclic Chemistry, 2011, 14 (9): 3676-3687.

58. Sheng-Hong Kang, Bao-an Song, Jian Wu, Min He, De-Yu Hu, Lin-hong Jin, Song Zeng, Wei Xue, Song Yang. Design, synthesis and insecticidal activities of novel acetamido derivatives containing N-pyridylpyrazole carboxamides[J]. European Journal of Medicinal Chemistry, 2013, 67,14-18.

59. Jian Wu, Baoan Song* Research progress of anti-virus agents for plants in China, SCIENTIA SINICA Chimica,2016, 46(11), 1165-1179 (in Chinese).

60. Fang-Zhou Xu, Yan-Yan Wang, Yun-Ying Zhu, Jia-Hui Shao, Gang Yu, Wei Xue, Jian Wu*, Hui-Bing Wu, Jun Shi, Synthesis and biological activity of novel sulfone derivatives containing a [1,2,4]triazolo[4,3-a]pyridine moiety[J]. Phosphorus, Sulfur, and Silicon and the Related Elements, 2017, 192(7), 850-855.

发明专利

1. 吴剑, 罗德霞, 郭声鑫, 代阿丽, 何凤, 陈顺红. 含α-羰基酰胺结构的醚类乙酰胺衍生物及其应用, CN201910809656.0；申请日：2019-08-29；授权公告日：2023-03-21.

2. 吴剑, 王艳艳, 徐方舟, 罗德霞, 郭声鑫, 代阿丽, 何凤, 陈顺红. 一种含三氟甲基吡啶二甲酰胺的席夫碱的衍生物及其应用, 申请(专利)号：CN 201910810123.4；申请日：2019-08-29；授权公告日：2022-09-23

3. 吴剑, 张仁凤, 郭声鑫, 陈顺红, 魏盼盼, 郑志国.一种阿魏酸酰胺衍生物及其合成方法, 申请(专利)号：CN 202110537257.0；申请日：2021-05-18；授权公告日：2022-07-01.

4. 徐方舟, 吴剑, 罗德霞, 郭声鑫, 何凤, 张仁凤, 陈顺红. 一种含三氟甲基吡啶的酰基硫脲或酰基脲类衍生物及其应用，申请(专利)号：CN 201910810477.9；申请日：2019-08-29,  授权公告日：2022-05-03

5. 吴剑, 王艳艳, 徐方舟, 寻曦炜, 黎泽莲, 罗德霞, 陈顺红, 薛伟. 一种N-杂环酰胺衍生物的合成方法. CN 201811093557.9；申请日：2018-09-19；授权公告日：2022-02-18.

6. 吴剑, 徐方舟, 王艳艳, 寻曦炜, 黎泽莲, 罗德霞, 陈顺红, 薛伟. 一种α-羰基酰胺衍生物的制备方法. 申请(专利)号：CN 201811016732.4；申请日：2018-09-03；授权公告日：2021-03-02

7. 吴剑, 徐方舟, 王艳艳, 罗德霞, 薛伟. 一种三氟甲基吡啶联噁二唑(醚)类衍生物及其应用. 申请(专利)号：CN201810060462.0；申请日：2018-01-22；授权公告日：2020-12-18

8. 吴剑, 余刚, 张建, 陈顺红, 何凤, 薛伟. 一种醚类化合物在促进植物生长方面的应用. 申请(专利)号：CN 201811094170.5；申请日：2018-09-19；授权公告日：2020-10-27

9. 吴剑, 徐方舟, 薛伟, 宋宝安, 刘登曰, 陈吉祥, 胡德禹, 杨松. 吡唑[3,4-d]嘧啶酮席夫碱类化合物在制备抗植物病毒剂中的应用. 申请(专利)号：CN 201610490135.X申请日：2016-06-29；授权公告日：2018-11-30.

10. 吴剑, 徐方舟, 薛伟, 刘登曰, 陈吉祥. 5-氨基-1H-吡唑[3,4-d]嘧啶-4(5H)-酮类化合物在制备抗植物病毒剂中的应用. 申请(专利)号：CN 201610463022.0；申请日：2016-06-23；授权公告日：2018-10-23.

11. 吴剑, 宋宝安, 薛伟, 胡德禹, 杨松, 杜显丽, 骆礼军, 马娟, 史庆才. 一种制备2,3-二氢喹唑啉-4(3H)-酮类衍生物的方法. 申请(专利)号：CN 201310501589.9；申请日：2013-10-23；授权公告日：2016-06-08

12. 宋宝安, 吴剑, 杨松, 金林红, 岳敏, 杰杰乌, 王贞超, 胡德禹. 含杂环酰胺结构的酰腙及肟酯类化合物及其应用. 申请(专利)号：CN 201010560706.5；申请日：2010-11-26；授权公告日：2014-04-02

13. 宋宝安, 吴剑, 杨松, 金林红, 岳敏, 杰杰乌, 王贞超, 胡德禹. 一类酰腙和酰肼衍生物及其应用. 申请(专利)号：CN 201010560727.7；申请日：2010-11-26；授权公告日：2013-04-17.

14. 宋宝安, 吴剑, 薛伟, 陈鹏丽, 杨松, 曾松, 胡德禹, 王贞超, 徐维明. 1,5-二取代芳基-1,4-戊二烯-3-酮肟醚类化合物及其制备方法和杀虫活性应用.申请(专利)号：CN 201010272708.4；申请日：2010-09-06；授权公告日：2012-06-27.

代表性国际会议报告

1. Xu Fangzhou, Wang Yanyan, Yu Gang, Wang Fenghua, Wu Jian *. A Facile Selective Synthesis of Spiro[indoline-3,9'-xanthene] Derivatives Based on Acidic/Basic Condition in Water, International Conference on New Challenges in Organic Synthesis, International Conference on Organic Chemistry, Guangzhou, China, 2016.11.26-2016.11.29.

2. Wu Jian*. Synthesis and Insecticidal Activities of novel Ppyrazole Amides containing Hydrazone Substructures., 4th International Symposium on Pesticide and Environmental Safety; 5th Pan Pacific Conference on Pesticide Science; 8th International Workshop on Crop Protection Chemistry and Regulatory Harmonization., Beijing, 2012.9.17-2012.9.20.

3. Wu Jian*, Song Baoan. Current Situation and Prospect of Green Development for Pesticide in China. The 2nd International Conference on Insect Pest Management. Guiyang, China. 2019.07.28-2019.07.31.

4. Wu Jian*, Song Baoan. Current Situation and Prospect of Green Development for Pesticide in China. The China ASEAN Advanced Forum on Agrochemicals. Nanning, China. 2019.09.25-2019.09.26.

5. Wu Jian*, Current Situation and Prospect of Green Development for Pesticide in China, The Second International Conference On Green Protection Innovation. Guiyang, China. 2019.10.20-2019.10.23.

6. Wu Jian*, Song Baoan. Innovation of agrichemicals for plant disease: The current situation and future. ACS Fall 2020 Virtual Meeting & Expo, Los Angeles USA (Online), 2020.8.16-2020.8.20.

7. Wu Jian*. The Current Situation and Prospect of Agrochemical Innovatin for Plant Diseases. Sino-European Plant Protection Young Scientists Forum – Utilization and Protection of Agricultural Crops in the Post-Covid-19 Era, Guiyang, China (Online), 2020.12.09-2020.12.12.

奖励/荣誉情况

1. 2023年，国家教学成果二等奖，植物保护专业“农生化交叉、产教研融合”人才培养模式的构建与实践，4/13；

2. 2020年，中国石油与化学工业联合会优秀出版物奖-图书奖一等奖，农药产业，1/5；

3. 2021年，第四届贵州省研究生教育成果特等奖，新时代农药学科创新型人才培养体系的构建与实践，3/7；

4. 2021年，贵州省科技进步一等奖，茶园主要病虫草害绿色高效防控技术体系创建与应用，7/9；

5. 2022年，大北农科技奖一等奖，茶园病虫草害绿色防控关键技术研究，5/10；

6. 2021年，贵州省“最美科技工作者”，1/1；

7. 2022年，第十届贵州省高等教育教学成果特等奖，植物保护专业人才培养模式的改革与实践，3/8；

8. 2023年，贵州大学2022年度“大北农奖”——优秀教师奖；

9. 2020年，贵州大学“书记校长特别嘉奖”；

10. 2020年，贵州大学“清原绿色农药奖”；

11. 2023年，贵州大学2022年度“书记校长特别嘉奖”。