伍星星教授简历

个人简介

伍星星，教授，博士生导师，入选国家海外高层次青年人才项目，贵州大学学术学科带头人，卓越人才-科技咨询专家，欧盟“玛丽.居里”学者，《农药学学报》期刊首届青年编委等。2017年毕业于新加坡南洋理工大学化学与生物化学专业，获哲学博士学位，2018年至2022年在瑞士巴塞尔大学从事博士后研究。长期致力于发展绿色、高效不对称催化合成方法，搭建了一系列通用性的原创不对称制备技术模型，实现了多种农药活性手性化合物库的高效构建。以第一作者/通讯作者在Nature Catalysis, Nature Commun, Science Advances, J. Am. Chem. Soc, Angew. Chem. Int. Ed., Trends in Chemistry等高水平期刊上发表论文40余篇。部分成果获2023年清原绿色农药优秀教师奖，英国皇家化学会Chem. Commun. Emerging Investigators (2025) 和Org. Chem. Front. Emerging Investigators (2025), 瑞士化学会-Helvetica 2nd Prize (2023)，2017年国家留学基金委“优秀自费留学生奖学金”等。

工作经历

2022年5月——至今      贵州大学     教授

教育经历

2018年2月——2018年5月    瑞士巴塞尔大学    “玛丽.居里”学者博士后（导师：Prof. Christof Sparr）

2018年2月——2018年5月    新加坡南洋理工大学       研究助理

2013年8月——2017年11月    新加坡南洋理工大学    博士（导师：Prof. Yonggui Robin Chi）

2006年9月——2013年6月      华东师范大学  本科/硕士研究生（导师：张俊良教授）

学术兼职

2022年7月——2025年6月        《农药学学报》青年编委

2025年8月——至今        《Green Synthesis and Catalysis》青年编委

教学工作

本科生课程：

1. 基础有机化学1-1（主讲）

2. 基础有机化学实验1-1（主讲）

3.国际班College Chemistry a-1（主讲）

4. College Chemistry a-2（主讲）

5. Inorganic Chemistry a-1（主讲）

6. Inorganic Chemistry a-2（主讲）

7. Inorganic Chemistry Experiment a-1和a-2（主讲）

8. College Chemistry Experiment a-1（主讲）

研究生课程：

1.专业英语（双语，主讲）

研究方向

1. 有机化学，不对称催化，有机小分子催化，自由基化学等；

2. 农药活性分子设计与绿色农药创制；

科研项目

1. 优秀青年科学基金海外项目（主持）

2. 贵州大学科技咨询专家科研启动项目：植物化学保护[(2022)47]（主持）

3. 国家自然科学基金面上项目：惰性C（sp3）-H键直接转化与应用 （主持）

4. 贵州省科技厅基础研究项目：手性含磷化合物不对称构建及农药活性研究（主持）

5. 区域联合基金重点项目（参与）

代表性论著

已在国内外发表学术论文五十余篇；撰写英文书籍章节2章。

部分代表性论文：

1. Yanyan Wang, Kuohong Chen, Fengrui Che, Sha Zhao, Pinpin Feng, Qiang Zhao, Donghui Wei,* Xingxing Wu,* and Yonggui Robin Chi,* NHC-catalyzed covalent activation and control of P (V)-stereogenic phosphorus centers via phosphonyl azolium intermediates. Chem. 2025,DOI: 10.1016/j.chempr.2025.102586

2. Qiang Xiong, Minghong Liao, Sha Zhao, Sitian Wu, Ya Hong, Yonggui Robin Chi, Xinglong Zhang*, Xingxing Wu*, Asymmetric Synthesis of S (IV)‐Stereogenic Sulfinimidate Esters by Sulfinamide Activation. Angew. Chem. Int. Ed. 2025, 64, e202500170. (Hot paper)

3. Minghong Liao, Shiqing Huang, Qiang Xiong, Zhongfu Luo, Sha Zhao, Taiyou Xu, Xingxing Wu*, Asymmetric catalytic reductive transformation of S (VI) to S (IV) for modular access to S (IV)-stereogenic sulfilimine derivatives, Science Advances2025, 11, eadx2509.

4. Benpeng Li, Junyuan Hu, Zhengtao Xu, Minghong Liao, Prof. Dr. Yonggui Robin Chi, Prof. Dr. Xingxing Wu*, Control Over S(VI) Stereogenicity for the Asymmetric Synthesis of Sulfonimidoyl Derivatives by Isothiourea-Catalyzed Covalent Activation of Sulfur(VI) Atoms, Angew. Chem. Int. Ed. 2025, e202510595. (Hot paper)

5. Chunyan Jian, Xuan Huang, Hongyan Long, Minghong Liao, Xingxing Wu*, Heteroarylation of Sulfenamides for Modular Synthesis of Antimicrobial Sulfilimines via Sulfinimidoyl Fluoride Intermediates, Org. Lett.2025, 27 (21), 5464-5470.

6. Yaoluo Hu, Ya Hong, Yuting Zheng, Yi Huang, Jixiang Chen,* and Xingxing Wu*. Synthesis of Antimicrobial Active 9,10-Phenanthrenequinones by Carbene Organocatalytic Tandem Reactions. Org. Chem. Front. 2025, 12 (6), 1778-1785.

7. Yijie Long,Pinpin Feng, Hongyan Long,Yi Huang and Xingxing Wu*. Stable sulfonate esters as C1-synthons for cyclopropanation reaction to access antimicrobial active 3, 3'-spirocyclopropyloxindoles Org. Chem. Front. 2025, 12(13), 3863-3869.

8. Sha Zhao, Xiuli Wu, Zhengtao Xu, Songyan Ye, Xingxing Wu*. Metal-Free Alkane Functionalization by Organocatalytic and Photoinduced Methods. The Chemical Record, 2025,e202400265.

9. Qin Xiong, Minghong Liao, Gangyu Wang, Hai Shi, and Xingxing Wu*. Synthesis of Chiral N-Free Sulfinamides by Asymmetric Condensation of Stable Sulfinates and Ammonium Salts. Chem. Commun. 2025, 61(14), 3017-3020

10. Yuting Zhao, Xin Ji, Yuanjing Xiao, Xingxing Wu, Lu Liu, Chem. Commun. 2025, 61 (27), 5162-5165.

11. Xiuli Wu, Qiang Zhao, Yuting Zheng, Yijie Long, Xingxing Wu*, Assembly of Molecular Complexity by Carbene Organocatalytic Multicomponent Reactions Involving α, β‐Unsaturated Aldehydes, Eur. J. Org. Chem. 2025, 28 (23), e202500220.

12. Minghong Liao, Yonggui Liu, Hongyan Long, Qin Xiong, Xiaokang Lv,Zhongfu Luo, Xingxing Wu*, Yonggui Robin Chi*. Enantioselective sulfinylation of alcohols and amines by condensation with sulfinates. Chem2024, 10(5), 1541–1552.

13. Xiaokang Lv,Fen Su, Hongyan Long, Fengfei Lu,Yukun Zeng, Minghong Liao, Fengrui Che, Xingxing Wu*, Yonggui Robin Chi*. Carbene Organic Catalytic Planar Enantioselective Macrolactonization. Nat. Commun. 2024, 15(1), 958.

14. Benpeng Li, Junyuan Hu, Minghong Liao, Qin Xiong, Yaqi Zhang, Yonggui Robin Chi, Xinglong Zhang,* and Xingxing Wu*. Catalyst Control over S(IV)-stereogenicity via Carbene-derived Sulfinyl Azolium Intermediates. J. Am. Chem. Soc. 2024, 146(36), 25350–25360.

15. Fengrui Che, Junyuan Hu, Minghong Liao, Zhongfu Luo, Hongyan Long, Benpeng Li, Yonggui Robin Chi, and Xingxing Wu*. Synthesis of P(V)-Stereogenic Phosphorus Compounds via Organocatalytic Asymmetric Condensation.J. Am. Chem. Soc.2024, 146(49), 33763–33773.

16. Zhongfu Luo, Minghong Liao, Wei Li, Sha Zhao, Kun Tang, Pengcheng Zheng, Yonggui Robin Chi, Xinglong Zhang,* and Xingxing Wu*. Ionic Hydrogen Bond-Assisted Catalytic Construction of Nitrogen Stereogenic Center via Formal Desymmetrization of Remote Diols. Angew. Chem. Int. Ed. 2024, 63(31), e202404979. (Hot Paper)

17. Hongyan Long, Sha Zhao, Chunyan Jian, Xiuli Wu, Fengfei Lu, Minghong Liao, Fengrui Che, Xingxing Wu*, Yonggui Robin Chi*. Carbene-catalyzed Enantioselective Seleno-Michael Addition as Access to Antimicrobial Active Se-containing Heterocycles. Sci. China. Chem.2024, 67(7), 2199–2205.

18. Kun Tang, Fen Su, Shijie Pan, Fengfei Lu, Zhongfu Luo, Fengrui Che, Xingxing Wu*, Yonggui Robin Chi*. Enones from Aldehydes and Alkenes by Carbene-catalyzed Dehydrogenated Couplings. Chin. Chem. Lett.2024, 35(9), 109495.

19. Kunpeng Teng, Qian Liu, Meng Zhang, Hira Naz, Xingxing Wu*, Yonggui Robin Chi.* Design, Enantioselective Synthesis of Chiral Pyranone Fused Indole Derivatives with Antibacterial Activities against Xanthomonas oryzae pv. oryzae for Protection of Rice. J. Agric. Food Chem. 2024, 72(9), 4622-4629.

20. Xiaoqun Yang, Shichun Jiang, Meng Zhang, Tingting Li, Zhichao Jin, Xingxing Wu* and Yonggui Robin Chi.* Discovery of novel piperidine-containing thymol derivatives as potent antifungal agents for crop protection. Pest Manag. Sci.2024, 80(10), 4906–4914.

21. Fengfei Lu, Fen Su, Shijie Pan, Xiuli Wu, Xingxing Wu*, and Yonggui Robin Chi*. N-Heterocyclic Carbene Enabled Functionalization of Inert C(Sp3)-H Bonds via Hydrogen Atom Transfer (HAT) Processes. Chem. Eur. J.2024, 30(47), e202401811.

22. Tingwei Shen, Jiamiao Jin, Jia Song, Hira Naz, Zhichao Jin, Yonggui Robin Chi, Xingxing Wu*. Design, enantioselective synthesis and antiviral activities against potato virus Y of axially chiral thiazine derivatives. J. Heterocyclic. Chem.2024, 61(3), 421–429.

23. Fen Su, Juan Zou, Xiaokang Lv, Fengfei Lu, Yijie Long, Kun Tang, Benpeng Li, Huifang Chai, Xingxing Wu*, Yonggui Robin Chi*. Carbene-Catalyzed Intermolecular Dehydrogenative Coupling of Aldehydes with C(sp³)−H Bonds. Angew. Chem. Int. Ed.2023, 62(23), e202303388. (Selected as VIP paper)

24. Fen Su, Fengfei Lu, Kun Tang, Xiaokang Lv, Zhongfu Luo, Fengrui Che, Hongyan Long, Xingxing Wu*, Yonggui Robin Chi.* Organocatalytic C−H Functionalization of Simple Alkanes. Angew. Chem. Int. Ed. 2023, 62(45), e202310072.

25. Yanyan Wang, Yonggui Liu, Sha Zhao, Yijie Long, Xingxing Wu*. Catalyst-controlled Stereoselective Carbon-heteroatom Bond Formations by N-Heterocyclic Carbene (NHC) Organocatalysis. Org.Chem. Front.2023, 10(17), 4437–4458. (Hot article)

26. Hongling Wang, Fen Su, Yanyan Wang, Xingxing Wu* and Yonggui Robin Chi*. Direct coupling of inert C–H bonds in NHC organocatalysis. Org. Chem. Front.2023, 10(20), 5291–5295. (Hot article)

27. Yonggui Liu, Yanyan Wang, Xingxing Wu*, Yonggui Robin Chi*. Exploring Molecular Complexity by N-Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity. Chem. Record. 2023, 23(7), e202200219.

28. Hongling Wang, Xingxing Wu*, Yonggui Robin Chi*. Distal Difunctionalization of Aldehydes via the Triplet State of Breslow Intermediates. Chem. Catal. 2022, 2(12), 3275-3277.

29. Yonggui Liu, Yanyan Wang, Xingxing Wu*, Yonggui Robin Chi*. Exploring Molecular Complexity by N-Heterocyclic Carbene Organocatalysis: New Activation and Reaction Diversity.Chem. Record. 2022, 22(12), e202200219.

30. Book chapter: Xingxing Wu, Yonggui Liu, Zhichao Jin. Organocatalytic Dynamic Kinetic Resolution (Chapter 3) in Dynamic Kinetic Resolution (DKR) and Dynamic Kinetic Asymmetric Transformations (DYKAT) (Eds. J.-E. Bckvall), 2022, Georg Thieme Verlag KG, Stuttgart, Germany.

31. Xingxing Wu, Christof Sparr*, Retrosynthetic polyketide disconnections for unnatural aromatics, Trends in Chemistry, 2022, 4(5), 367−370.

32. Xingxing Wu, Christof Sparr*. Stereoselective Synthesis of Atropisomeric Acridinium Salts by the Catalyst-Controlled Cyclization of ortho-Quinone Methide Iminiums. Angew. Chem. Int. Ed., 2022, 61(19), e202201424.

33. Xingxing Wu,⁺ Reto Witzig,⁺(⁺ denotes equal contribution)Rodolphe Beaud, Christian Fischer, Daniel Häussinger, Christof Sparr*. Catalyst Control over Sixfold Stereogenicity. Nature Catalysis, 2021, 4(6), 457−462.

34. Xingxing Wu,⁺ Liejin Zhou,⁺(⁺ denotesequal contribution)Rakesh Maiti, Chengli Mou, Lutain Pan*, Yonggui Robin Chi*. Sulfinate and Carbene Co-catalyzed Rauhut-Currier Reaction for Enantioselective Access to Azepino[1,2-a]indoles. Angew. Chem. Int. Ed. 2019, 58, 477−481.

35. Xingxing Wu, Lin Hao, Yuexia Zhang, Maiti Rakesh, Rambabu N. Reddi, Song Yang, Bao-An Song, Yonggui Robin Chi*. Construction of Fused Pyrrolidines and β-Lactones by Carbene-Catalyzed C−N, C−C, and C−O Bond Formations. Angew. Chem. Int. Ed. 2017, 56, 4201−4205.

36. Xingxing Wu, Yuexia Zhang, Yuhuang Wang, Jie Ke, Martin Jeret, Rambabu N. Reddi, Song Yang, Bao-An Song*, Yonggui Robin Chi*. Polyhalides as Efficient and Mild Oxidants for Oxidative Carbene Organocatalysis by Radical Processes. Angew. Chem. Int. Ed. 2017, 56, 2942−2946;

37. Xingxing Wu,⁺ Bin Liu,⁺(⁺ denotesequal contribution)Yuexia Zhang, Martin Jeret, Honglin Wang, Pengcheng Zheng, Song Yang*, Bao-An Song, Yonggui Robin Chi*. Enantioselective Nucleophilic β-Carbon-Atom Amination of Enals: Carbene-Catalyzed Formal [3+2] Reactions. Angew. Chem. Int. Ed. 2016, 55, 12280−12284;

38. Liejin Zhou,⁺Xingxing Wu,⁺ (⁺ denotesequal contribution)Xing Yang, Chengli Mou, Runjiang Song, Shuyan Yu, Huifang Chai, Lutai Pan*, Zhichao Jin, Yonggui Robin Chi*. Gold and Carbene Relay Catalytic Enantioselective Cycloisomerization/Cyclization Reactions of Ynamides and Enals. Angew. Chem. Int. Ed. 2020, 59, 1557−1561;

39. Xingxing Wu, Wei Zhou, Hai-Hong Wu*, Junliang Zhang*. Enantioselective [3+2] cycloaddition of azomethine ylides and aldehydes via Ni/bis(oxazoline)-catalyzed ring opening of N-tosylaziridines through a chirality transfer approach. Chem. Commun. 2017, 53, 5661−5664;

40. Xingxing Wu, Lei Li, Junliang Zhang*. Nickel(II)-catalyzed diastereoselective [3+2] cycloaddition of N-tosyl-aziridines and aldehydes via selective carbon–carbon bond cleavage. Chem. Commun. 2011, 47, 7824−7826.

奖励/荣誉情况

皇家化学会Chem. Commun. Emerging Investigators 新锐科学家 (2025)

Org. Chem. Front. Emerging Investigators 新锐科学家 (2025)

2023年，贵州大学-清原绿色农药优秀教师奖；

2023年，瑞士化学会-Helvetica 2^nd Prize (2023);

2019-2021，欧盟研究委员会-“玛丽.居里学者“；

2017年，国家留学基金委-国家优秀自费留学生奖学金。